Cloud computing is an emerging and fast-growing technology in the field of healthcare industries. It provides a connected, accessible, and collaborative environment for all the stakeholders of the healthcare system. In the present time, health organizations are focusing towards increasing the quality of patient care or health information systems through digitalization. Despite several risks in implementation, compliance, availability, security, etc., cloud computing plays a major role in healthcare due to high storage capability, scalability, collaboration, and most importantly, provisioning of information when required without any delay. The performance of the healthcare system always depends on accessibility, sharing, storage, processing, and analysis of data. This chapter identifies the state of the research and identifies the established framework. This chapter addresses the different challenges and opportunities of adopting a cloud environment as well as related issues like privacy, security, and accountability.