Indoor air quality (IAQ) is not only a determinant of occupational health but also influences all indoor human behaviours. In most university establishments, laboratories are also used as classrooms. On one hand, indoor environment quality (IEQ) conditions supervision in laboratories is relevant for experimental activities. On the other hand, it is also crucial to provide a healthy and productive workplace for learning activities. The proliferation of cost-effective sensors and microcontrollers along with the Internet of Things (IoT) architectures enhancements, enables the development of automatic solutions to supervise the Laboratory Environmental Conditions (LEC). This paper aims to present a real-time IEQ-laboratory data collection system-based IoT architecture named iAQ Plus (iAQ+). The iAQ+ incorporates an integrated Web management system along with a smartphone application to provide a historical analysis of the LEC. The iAQ+ collects IAQ index, temperature, relative humidity and barometric pressure. The results obtained are promising, representing a meaningful contribution for IEQ supervision solutions based on IoT. iAQ+ supports push notifications to alert people in a timely way for enhanced living environments and occupational health, as well as a work mode feature, so the user can configure setpoints for laboratory mode and schoolroom mode. Using the iAQ+, it is possible to provide an integrated management of data information of the spatio-temporal variations of LEC parameters which are particularly significant not only for enhanced living environments but also for laboratory experiments.