Smart prototype for an electronic color sensor device for visual simultaneous detection of macrofuran based on a coated paper strip

Abstract

Nowadays, in the clinical, pharmaceutical, and environmental sectors, the development of facile and sensitive analytical methods and/or innovative devices for the follow-up and detection of antibiotics and pharmaceutical formulations, in general, are urgently needed and still challenging. This work declared three vital applications for broad-spectrum nitrofurantoin (macrofuran) antibiotic detection and quantification: A colorimetric method, a coated paper strip-based nano-lanthanum complex prototype and fabrication of smart electronic color sensor device-based coated paper strips. The colorimetric method showed a significant response upon increasing the concentration of the nitrofurantoin in a range between (1.0–100.0 ng/mL) via a visual color change from orange-yellow to red colors degree with detection and quantification limits of 0.175 and 0.53 ng/mL, respectively, whereas the nano-lanthanum complex coated paper strip prototype showed qualitative on-site sensing for nitrofurantoin via naked eye color changes which can be detected anywhere. Moreover, a smart prototype for detecting macrofuran in the means of paper color change in the RGB color component extraction algorithm and the grayscale projection value processing algorithm was fabricated. The change in RGB color on the coated paper strip was detected using an electronic color sensor device. The developed colorimetric method, coated paper strip, and the electronic color sensor device prototype exhibited fast, simple, costless, and selective towards macrofuran over the competing analyzed. As well as, showed good applicability in the different real samples spiked with different concentrations of macrofuran. Graphical abstract

Simple and affordable colorimetric sensing strips for quantitative determination of total manganese in porewater samples

“…They used LEDs as light sources and a DVD disk as a light‐dispersing element. Furthermore, devices similar to ours have been recently designed and applied to the detection of antibiotics (Sheta et al 2022) or to pH measurements by means of chemometric procedures (Pazzi et al 2022). An advantage of our system is that it can measure six strips at a time.…”

A novel test device and quantitative colorimetric method for the detection of human chorionic gonadotropin (hCG) based on Au@Zn–salen MOF for POCT applications

“…4 In many instances, patients need immediate results from diagnostic tests performed in medical laboratories, even though these tests oen take a long time, necessitate multiple stages of preparation for the sample, and call for sophisticated tools for infrastructural construction and staff with extensive training. 5,6 In countries with few medical resources, POCT has emerged to be an invaluable tool for both patients and their doctors. For example, various benets of POCT have led to annual sales of more than three and a half million euros in Europe.…”