This article explores the contributions of—and constraints faced by—small and medium enterprises (SMEs) owned by mainland Chinese immigrant entrepreneurs in Malaysia using qualitative research and primary data gathered from five cases. It was found that Chinese immigrant SMEs make significant contributions to the host economy in terms of employment, diverse products and services, exports, innovation, micro foreign direct investment (FDI) and global linkages. Of these, employment creation and exports appear to be their most important contributions. They face various constraints, some of which are largely the same as those faced by local entrepreneurs. However, they additionally face some specific constraints which local entrepreneurs do not, such as language barrier, lack of financial support in the growth stage, lack of government assistance, and onerous bureaucratic problems, such as tax and visa requirements. The findings suggest that the government should create a special department to formulate tailor-made policies and incentives to support immigrant-owned SMEs, so that their contribution to the future economic development of Malaysia can be further strengthened and monitored.