“…The rates may be lower in these latter groups because, although there is considerable variability across programs, more stringent psychosocial criteria may be applied in the transplant candidate selection process than are applied for kidney candidates (63,64) and/or because the consequences of graft loss are more severe: unlike kidney recipients who may return to dialysis, the options for prolonging life for most heart or liver recipients are considerably more limited. Yet the rates of just 14 to 15 nonadherent heart recipients or 7 liver recipients per 100 PPY may be clinically unacceptable as well: all of these rates are at least double the rate of tobacco use, which even at its relatively lower level of 3 to 4 patients per 100 PPY, is still a powerful contributor to posttransplant morbidity and mortality (15,18,65,66).…”