Smoking habits amongst patients with psoriasis and the effect of smoking on clinical and treatment‐associated characteristics: A cross‐sectional study

Abstract

Background Psoriasis is a multifactorial, chronic inflammatory skin disease where genetic and environmental factors play a role in the pathogenesis. Smoking is one of the critical environmental factors triggering psoriasis. Objective The purpose of the present study was to analyse the smoking habits of patients with psoriasis and the effect of smoking on disease characteristics. Methods One hundred and thirty‐three patients who applied to the department of Dermatological and Venereal Diseases, Ankara Numune Education and Research Hospital, between May 2018 and May 2019 and were diagnosed with psoriasis participated in the study. Clinical, demographical, and treatment‐related characteristics, and smoking habits of patients were recorded. Results Sixty‐seven point six percent of psoriasis patients were smokers. The presence of moderate to severe psoriasis (P = .028), nail involvement (P = .004), administration of systemic treatment (P = .024) and additional cardiovascular disease (P = .038) frequencies was higher in smokers compared to non‐smokers. Besides, a positive correlation was observed between the amount of smoking and psoriasis area and severity index (PASI) (P = .003; r = .32). Conclusions Smoking has many negative effects on patients with psoriasis including higher PASI levels, increased frequency of nail involvement, and cardiovascular diseases. Questioning cigarette smoking in psoriatic patients and supporting smoking cessation may contribute to reducing the adverse impact of smoking on psoriasis.

An Observational Study of 147 Psoriasis Patients: Overweightness and Obesity as a Significant Clinical Factors Correlated with Psoriasis

“…On the other hand, a very-lowcalorie ketogenic diet, through antioxidant and anti-inflammatory effects and subsequent weight loss, significantly enabled better psoriasis disease control [42]. In comparison to the general population, a substantial percentage (55.78%) of psoriatic patients were declared to be past or current smokers, which contributes to a more severe course of the disease, as well as to the development of cardiovascular disease and a higher mortality rate [43][44][45][46][47]. Owczarczyk-Saczonek et al noted a higher prevalence of tobacco addiction among Polish men with psoriasis [48].…”

The Impact of Hypertension, Diabetes, Lipid Disorders, Overweight/Obesity and Nicotine Dependence on Health-Related Quality of Life and Psoriasis Severity in Psoriatic Patients Receiving Systemic Conventional and Biological Treatment

“…Among smokers, 29.3% of the patients had moderate/severe psoriasis ( p = 0.028). The median PASI score was 5.9 for smokers compared to 2.3 in non-smokers ( p = 0.003) [ 23 ]…”

Triggers for the onset and recurrence of psoriasis: a review and update

“…Smoking intensity and duration may have a dose-dependent effect on the incidence of psoriasis [ 197 , 198 ]. As an independent risk factor for the development of psoriasis, smoking has many negative effects on psoriasis patients, including a higher PASI score, elevated nail involvement, and the development of cardiovascular diseases [ 199 ].…”