Smooth muscle cell heterogeneity in intimal thickenings of various genesis and in organized thrombi

Abstract

collagen fibers is one of the atherosclerosis markers. Taken together, our observations indicate that experimental HC induces pronounced atherosclerotic changes in pial arteries. Pat., 42, No. 6, 26-33 (1980). 3. K. G. Volkova, Arkh. Biol. Nauk, 33, No. 3-4, 581-602 (1933 Psikhiatr., 87, No. 7, 992-995 (1987). REFERENCES Smooth Muscle Cell Heterogeneity in lntimal Thickenings of Various Genesis and in Organized Thrombi B. V. Shekhonin, E. M. Tararak, and A. E. ZotikovTranslated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 8, pp. 222-227, August, 1996 Original article submitted May 25, 1995 A population of smooth muscle cells heterogeneous by the expression of myosin, h-caldesmon, and calponin is identified by indirect immunofluorescence in the intima of normal aorta and femoral artery, in the subendothelium in atherosclerosis and Takayasu's disease, and in organized thrombi. The similarity of the extracellular matrix in various forms of arteriosclerosis implies that its hyperproduction is a typical response of smooth muscle cells.