Let X be a Banach space with a fundamental biorthogonal system and let Y be the dense subspace spanned by the vectors of the system. We prove that Y admits a C ∞ -smooth norm that locally depends on finitely many coordinates (LFC, for short), as well as a polyhedral norm that locally depends on finitely many coordinates. As a consequence, we also prove that Y admits locally finite, σ-uniformly discrete C ∞ -smooth and LFC partitions of unity and a C 1 -smooth LUR norm. This theorem substantially generalises several results present in the literature and gives a complete picture concerning smoothness in such dense subspaces. Our result covers, for instance, every WLD Banach space (hence, all reflexive ones), ℓ ∞ (Γ) spaces for every set Γ, C(K) spaces where K is a Valdivia compactum, duals of Asplund spaces, or preduals of Von Neumann algebras. Additionally, under Martin Maximum MM, all Banach spaces of density ω 1 are covered by our result.