In this study, amphibian and reptile diversity in the province of Van (eastern Anatolia, Turkey) was surveyed. For this purpose, four herpetological excursions (20 days in total) were conducted covering all the districts of the province in 2014. In this paper, up-to-date herpetofaunal inventory of Van Province, including two urodelian, four anuran, two chelonian, 15 saurian (lizards), and 14 ophidian (snakes) species (six amphibians and 31 reptiles in total) is presented. To the best of our knowledge, Salamandra infraimmaculata, Heremites auratus, Dolichophis jugularis, Eirenis modestus, and Telescopus fallax were recorded for the first time in the province of Van. Additionally, the first published print record of Stellagama stellio in Van Province is presented. The major threat to the herpetofaunal diversity in surveyed habitats was found as human-origin habitat degradation. With the georeference database obtained in this study, it will be possible to determine the actual distribution ranges of the species and to guide decision-makers. The results of the study will provide a useful basis for future monitoring studies and distribution information will contribute to the conservation of the species of interest.