Snapshot EvaLuation oF Heart FaIlurE in TuRkey: Baseline Characteristics of SELFIE-TR

Yılmaz, Mehmet; Çelik, Ahmet; Çavuşoğlu, Yüksel; Bekar, Lütfü; Onrat, Ersel; Eren, Mehmet; Kutlu, Merih; Yalta, Kenan; Temizhan, Ahmet; Kiliçaslan, Barış; Güngör, Hasan; Açıkel, Mahmut; Demir, Mesut; Akdemir, Ramazan; Kılıç, Salih; Tokgözoğlu, Lâle

doi:10.5543/tkda.2019.66877

Cited by 13 publications

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“…This analysis is a prospective outcome analysis of a national registry, named SELFIE-TR, conducted at 23 sites representing 12 NUTS-1 regions of Turkey. The design and methodology of SELFIE-TR was published in the baseline characteristics paper (3). Patients were classified into two as acute (AHF) versus chronic HF (CHF) per protocol.…”

Section: Methodsmentioning

confidence: 99%

“…There are registries in different cardiovascular diseases including one recent registry evaluating the overall HF patient profile, representative of Turkey (3). With regard to the management of HF, observational and retrospective data from tertiary care centers in Turkey designated that overall prescription rates for beta blockers (BBs) and renin-angiotensin-aldosterone system (RAAS) blockers were acceptable; however, target dose was rarely achieved among patients with HF (4).…”

Section: Introductionmentioning

confidence: 99%

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Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey: Follow up data for mortality

et al. 2019

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Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality Objective: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided. Methods: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM. Results: There were 1054 patients with a mean age of 63.3±13.3 years and with a median follow-up period of 16 (7-17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores ≤1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year. Conclusion: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey: Follow up data for mortality

et al. 2019

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“…Even if the incidence of HFrEF and HFpEF is different, the incidence of HFmrEF in our country is similar to that in the international clinical studies conducted. 13 In two large-scale studies conducted in 2015 and 2016, the accepted rate of HFm-rEF in HF was within the range of 13-24%. [17][18][19] In Variables that fit the normal distribution were expressed as Mean±SD, variables that did not fit the normal distribution were indicated as median (minimum-maximum).…”

Section: Discussionmentioning

confidence: 98%

“…25 The SELFIE-TR study conducted in 2019, showing the snapshot of HF in our country, reported the mean age of the HFrEF group as 62.1±13.2, and the mean age of the HFmrEF group as 65.9±12.3. 13 In the study conducted on more than 1 million patients in America in the same year, the authors reported the mean age as 67.8±13.5 in the HFrEF group and 70.1±12.8 in the HFmrEF group. 23 These recent studies found that the mean age of the HFmrEF group was significantly higher than that of the HFrEF group.…”

Section: Discussionmentioning

confidence: 99%

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Single-Center Retrospective Evaluation of Clinical Features and Life Expectancy in Mid-Range/Reduced Left Ventricular Ejection Fraction Heart Failure Patients Who Died During Hospitalization

Dindaş¹,

Turgut²,

Yilmaz³

2020

Turkiye Klinikleri J Cardiovasc Sci

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Today, despite medical developments the frequency of heart failure is increasing. The current guidelines have categorized patients with heart failure (HF) by their phenotypes to better explain them. In our study, we aimed to compare the basic clinical features, drug treatment and the life expectancy in HF phenotypes who died during hospitalization. Material and Methods: 100 consecutive patients who admitted with HF between 2011 and 2018 and died of cardiac cause during last hospitalization were evaluated. Patients with left ventricle ejection fraction (LVEF) 41-49% and N-terminal pro-B type natriuretic peptide (NT-proBNP) level >125 pg/mL were classified in the study as HFmrEF. Patients with EF% ≤40 NT-proBNP level >125 pg/mL were classified in the study as HFrEF. There were 50 patients from each HF group. Patients' demographic features, major laboratory parameters, drug treatments and life expectancy were evaluated in retrospective analysis. SPSS version 17.0 program was used for statistical analysis. p<0.05 was considered statistically significant. Results: The LVEF values of HFrEF and HFmrEF patients were 30% (15-38) and 45% (40-49), respectively. There was no significant difference between groups in drug treatment. The life expectancy values of the groups were 15 (1-61) months in the HFmrEF group and 11 (1-49) months in the HFrEF group (p=0.043). Conclusion: In our study, it was concluded that the demographic characteristics of HFrEF and HFmrEF patients were different. The life expectancy in HFmrEF group was longer than in HFrEF group.

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The diagnostic value of chest X‐ray scanning by the help of Artificial Intelligence in Heart Failure (ART‐IN‐HF)

Celik,

Surmeli,

Demir

et al. 2023

Clinical Cardiology

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BackgroundTypical signs of heart failure (HF), like increased cardiothoracic ratio (CTR) and pleural effusion, can be seen on X‐ray. Artificial Intelligence (AI) can help in the early and quicker diagnosis of HF.ObjectivesThe study's goal was to demonstrate that the AI interpretation of chest X‐rays can assist the clinician in diagnosing HF.MethodsPatients older than 45 years were included in the study. The study analyzed 10 100 deidentified outpatient chest X‐rays by AI algorithm. The AI‐generated report was later verified by an independent radiologist. Patients with CTR > 0.5 and pleural effusion were marked as potential HF. Flagged patients underwent confirmatory tests, and those labeled as negative also underwent further investigations to rule out HF.ResultsOut of 10 100, the AI algorithm detected 183 (1.8%) patients with increased CTR and pleural effusion on chest X‐rays. One hundred and six out of 183 underwent diagnostic tests. Eighty‐two (77%) out of 106 were diagnosed with HF according to current guidelines. From the remaining 9917 patients, 106 patients were randomly selected. Nine (8%) out of them were diagnosed with HF. The positive predictive value of AI for diagnosing HF is 77%, and the negative predictive value is 91%. More than half (54.9%) of newly diagnosed patients had HF with preserved ejection fraction.ConclusionHF is a risky condition with nonspecific symptoms that are difficult to diagnose, especially in the early stages. Using AI assistance for X‐ray interpretation can be helpful for early diagnosis of HF especially HF with preserved ejection fraction.

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Snapshot EvaLuation oF Heart FaIlurE in TuRkey: Baseline Characteristics of SELFIE-TR

Cited by 13 publications

References 0 publications

Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey: Follow up data for mortality

Snapshot Evaluation of Acute and Chronic Heart Failure in Real Life in Turkey: Follow up data for mortality

Single-Center Retrospective Evaluation of Clinical Features and Life Expectancy in Mid-Range/Reduced Left Ventricular Ejection Fraction Heart Failure Patients Who Died During Hospitalization

The diagnostic value of chest X‐ray scanning by the help of Artificial Intelligence in Heart Failure (ART‐IN‐HF)

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