2016
DOI: 10.1002/prp2.234
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Snapshot of the prescribing practice for the clopidogrel and esomeprazole coprescription and cost evaluation of the application guidelines

Abstract: The antiplatelet clopidogrel and the proton pump inhibitor esomeprazole demonstrate a pharmacokinetic interaction through CYP2C19 that could translate into clinical inefficacy of clopidogrel. No medical consensus as to their coprescription has been reached, and different guidelines are available. We evaluated the prescribing practices at the Geneva University Hospitals (HUG) by measuring whether the coprescription was staggered as suggested by experts. We estimated the financial impact of different implementat… Show more

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Cited by 3 publications
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“…A few national and international studies have evaluated the prescribing patterns of clopidogrel in combination with PPIs before and after the FDA safety communication was published . In 2015, Guerin et al .…”
Section: Introductionmentioning
confidence: 99%
“…A few national and international studies have evaluated the prescribing patterns of clopidogrel in combination with PPIs before and after the FDA safety communication was published . In 2015, Guerin et al .…”
Section: Introductionmentioning
confidence: 99%