2023
DOI: 10.21055/0370-1069-2022-4-41-49
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SNP-Profiles of <i>Yersinia pestis</i> Strains of the Medieval Biovar from the Caspian Sea Region Plague Foci

Abstract: The SNP-typing method based on the detection of stable genetic markers in the genome, i.e., single nucleotide polymorphisms, is successfully used for genotyping of pathogenic microorganisms and can be applied for SNP-profiling of Yersinia pestis strains and molecular-genetic certification of focal areas. The aim of the study was to determine the SNP profiles of Y. pestis strains of the medieval biovar isolated in the Caspian Sea region plague foci in 1912–2015 and to develop a method for identifying unique SNP… Show more

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