Background: Self-efficacy to resist alcohol use is necessary to prevent relapse after treatment. However, the duration of patients stay in treatment and social anxiety are crucial in treatment outcomes of patients but its predictive role in selfefficacy to resist alcohol in the Ghanaian context is yet to be known.Methods: Sixty participants obtained through purposive sampling participated in the study. These participants were patients with an established diagnosis for alcohol use disorder within the three main public psychiatric institutions and a specialized alcohol rehabilitation clinic in Ghana. Participants' demographic information was analysed using frequencies while multiple linear regression was used to test the hypothetical idea of the study.Results: 55% of the sample had severe social anxiety, 53% had been in treatment for more than three months and 60% of participants in the study had low self-efficacy to resist alcohol. Also, social anxiety and duration of treatment significantly predicted self-efficacy to resist alcohol. 15% of the variation in self-efficacy to resist alcohol was explained by participants' social anxiety and duration in treatment.Conclusions: Social anxiety and duration of treatment are the key influence of self-efficacy to resist alcohol among inpatients receiving treatment for alcohol use disorder in Ghana.