2016
DOI: 10.1371/journal.pone.0146218
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Social-Biological Interactions in Oral Disease: A ‘Cells to Society’ View

Abstract: Oral diseases constitute a major worldwide public health problem, with their burden concentrating in socially disadvantaged and less affluent groups of the population, resulting in significant oral health inequalities. Biomedical and behavioural approaches have proven relatively ineffective in reducing these inequalities, and have potentially increased the health gap between social groups. Some suggest this stems from a lack of understanding of how the social and psychosocial contexts in which behavioural and … Show more

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Cited by 52 publications
(49 citation statements)
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“…Previous research has highlighted the ability of social conditions to "get under the skin" to affect one's biological systems and hence the body's ability to fend off disease. 9,10,23 The effect of socio-economic position observed in this analysis supports this concept, where social and economic conditions that determine an individual's position on the social hierarchy can potentially influence immune functions -indicated here by markers of systemic inflammation -and eventually affect one's risk of periodontal inflammation. Furthermore, our findings are consistent with previous studies emphasizing the role of socio-economic position in linking oral and systemic health outcomes.…”
Section: Discussionsupporting
confidence: 67%
See 1 more Smart Citation
“…Previous research has highlighted the ability of social conditions to "get under the skin" to affect one's biological systems and hence the body's ability to fend off disease. 9,10,23 The effect of socio-economic position observed in this analysis supports this concept, where social and economic conditions that determine an individual's position on the social hierarchy can potentially influence immune functions -indicated here by markers of systemic inflammation -and eventually affect one's risk of periodontal inflammation. Furthermore, our findings are consistent with previous studies emphasizing the role of socio-economic position in linking oral and systemic health outcomes.…”
Section: Discussionsupporting
confidence: 67%
“…8 Previous research has proposed that disease is not merely the product of cellular and molecular cascades taking place within the body, but rather the result of an interplay between social factors, such as socio-economic position, and biological ones, such as the immune system. 9,10 These were suggested to interact through various reciprocating pathways, eventually leading to an increased risk of oral and/or systemic conditions. 9 Given the growing interest in the role of social and living conditions in bringing about disease -most notably, the impact of socio-economic conditions on the mechanisms of inflammation -the need to understand the interplay between social and biological factors has continued to gain importance and is now being brought to the forefront of clinical and public health research.…”
mentioning
confidence: 99%
“…Another effect not measured here is related with the psychosocial pathways: negative emotions arising from feelings of shame or distress caused by perceptions of physical appearance and discomfort related to dental health could impact general health through the psycho‐neuro‐endocrine mechanisms related to the stress response systems …”
Section: Discussionmentioning
confidence: 99%
“…Tooth loss can also be linked to general health through other indirect mechanisms, for instance, by modifying eating behaviours and causing poor nutrition . Moreover, tooth loss can also be directly related to general health, via the inflammatory and immune responses . Evidence suggests that periodontal diseases (the main cause of tooth loss in adults) are a source of chronic inflammation that can have effects on systemic inflammation .…”
Section: Introductionmentioning
confidence: 99%
“…In this context, oral health can be thought of as part of the aging process. The quote provides a back-drop for consideration of how social determinants impact our lives [2] and how these factors could impact oral health [3] and influence health policy.…”
mentioning
confidence: 99%