Social Cognition and Cognitive Decline in Patients with Parkinson’s Disease

Alonso-Recio, Laura; Carvajal, Fernando; Merino, C.; Serrano, José María González

doi:10.1017/s1355617720001204

Cited by 23 publications

(33 citation statements)

References 78 publications

(105 reference statements)

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“…A relationship between affective ToM and visuospatial function was also shown, arguing that the second could explain the first even in early stages of PD [69]. Later, Alonso-Recio et al, [14] found an association between affective ToM (measured with RMET) and processing speed, memory, and EF.…”

Section: Relationship With Other Cognitive Functions and General Cognitive Functionmentioning

confidence: 88%

“…A wide variety of tools have been used to evaluate ToM in PD [12,14,52]. Some of the tests have shown good reliability and sensitivity in other neurodegenerative disorders such as the behavioral variant of frontotemporal dementia (bvFTD) [15].…”

Section: Clinical Assessment Of Tom In Pdmentioning

confidence: 99%

“…The first one observed that PD-MCI patients (diagnosed according to the Montreal Cognitive Assessment (MoCA) score < 26) performed worse than PD-CN and a HC group in affective ToM (measured with RMET). However, cognitive ToM was not evaluated [14]. The second study included 109 medicated and newly PD patients with and without MCI (PD-MCI cognitive diagnosis performed according to MoCA score < 26) and found that PD patients performed significantly worse than HC in cognitive and affective ToM.…”

Section: Relationship With Other Cognitive Functions and General Cognitive Functionmentioning

confidence: 99%

“…Such is the importance of the study of SC as a cognitive domain that the Diagnostic and Statistical Manual for Mental Disorders [13] considers it to be one of the six key domains of mental function that should be evaluated in MCI and dementia. Although there is some disagreement with respect to the components of SC, as some of them share similar characteristics [14], the most important and most widely studied in PD are theory of mind (ToM), empathy, and social perception [15].…”

Section: Introductionmentioning

confidence: 99%

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What Do We Know about Theory of Mind Impairment in Parkinson’s Disease?

Trompeta

Rodríguez

Gasca-Salas

2021

Behavioral Sciences

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Theory of mind (ToM) is a social cognitive skill that involves the ability to attribute mental states to self and others (what they think (cognitive ToM) and feel (affective ToM)). We aim to provide an overview of previous knowledge of ToM in Parkinson’s disease (PD). In the last few years more attention has been paid to the study of this construct as a non-motor manifestation of PD. In advanced stages, both components of ToM (cognitive and affective) are commonly impaired, although in early PD results remain controversial. Executive dysfunction correlates with ToM deficits and other cognitive domains such as language and visuospatial function have also been related to ToM. Recent studies have demonstrated that PD patients with mild cognitive impairment show ToM deficits more frequently in comparison with cognitively normal PD patients. In addition to the heterogeneity of ToM tests administered in different studies, depression and dopaminergic medication may also be acting as confounding factors, but there are still insufficient data to support this. Neuroimaging studies conducted to understand the underlying networks of cognitive and affective ToM deficits in PD are lacking. The study of ToM deficit in PD continues to be important, as this may worsen quality of life and favor social stigma. Future studies should be considered, including assessment of the patients’ cognitive state, associated mood disorders, and the role of dopaminergic deficit.

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Section: Relationship With Other Cognitive Functions and General Cognitive Functionmentioning

confidence: 88%

Section: Clinical Assessment Of Tom In Pdmentioning

confidence: 99%

Section: Relationship With Other Cognitive Functions and General Cognitive Functionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

What Do We Know about Theory of Mind Impairment in Parkinson’s Disease?

Trompeta

Rodríguez

Gasca-Salas

2021

Behavioral Sciences

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“…Specifically, previous research proposed that dorso-lateral prefrontal areas and nigrostriatal dopaminergic circuits damage results in cognitive decline, such as, inferencing mental states of other people. Likewise, damage to ventromedial, orbitofrontal prefrontal cortex and mesolimbic circuits could result in inability to infer emotional states in others (Alonso-Recio et al, 2020;Bodden, Dodel, & Kalbe, 2010;Koirala et al, 2019;Luo et al, 2014). Social-pragmatic abilities entail the capability of people to communicate in different contexts, as well as recognize and express communicative intentions (Bara, 2010, Coundouris et al, 2019.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Parkinson’s Disease on Social Communication: An Exploratory Questionnaire Study

Sharma¹,

Fleck²,

Winslow³

et al. 2021

Preprint

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Individuals with Parkinson’s Disease (PD) often show breakdown in the interpretation of pragmatic language meaning. However, there is no current standard of care for evaluating social communication dysfunction in PD which affects the persons with PD and their caregivers. Thus, we developed a questionnaire for individuals with PD to evaluate social communication difficulties. Objective: The aim of this study was to develop a questionnaire to demonstrate a need for comprehensive management guidelines for individuals with PD regarding social communication skills. This questionnaire will highlight the areas of deficit for the individuals with PD. Methods: Fifty-one people with self-reported Parkinson’s Disease answered 28 survey questions. These questions pertained to emotional expression and perception, social communication, sarcasm/humor, and pragmatic skills. Exploratory factor analysis and reliability analysis were performed to identify which items loaded onto the desired factor and to check the internal consistency of the items. Results: Persons with PD reported changes in emotional expression and perception, social communication, sarcasm and humor, and pragmatic skills domains post PD diagnosis. No correlations were found between age/time since diagnosis and emotional expression, social communication, sarcasm, and humor.Conclusion: The current study provides evidence that persons with PD experience social communication challenges. Therefore, it is crucial to increase awareness of these deficits in PD to recognize the impact of the disease on social communication.

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Social Cognition in Parkinson's Disease: A Case‐Control Study

Siripurapu

Verma

Biswas

et al. 2023

Movement Disord Clin Pract

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Background Social cognition is the study of how people make sense of themselves and others. Impairment in several domains of social cognition is increasingly being recognized in Parkinson's disease (PD). Objectives We aimed to study multiple domains of social cognition in Indian PD patients using a culturally appropriate, validated instrument. Methods We recruited 52 individuals with PD and 31 healthy volunteers (HV) and used the Social Cognition Rating Tools in Indian Setting (SOCRATIS) tool to assess theory of mind (ToM), attributional biases and social cue perception. Quality of life (QoL) was assessed using the PDQOL scale. Results Baseline characteristics were comparable between PD and HV. The mean (SD) FOT index (first order ToM index) was 0.86(0.18) in PD and 0.99(0.07) in HV [P < 0.001]. The PD group showed higher Externalizing Bias [EB, 4.42(3.91)], compared to HV [1.58(3.22), P = 0.001]. The mean (SD) Faux Pas Composite Index (FPCI ALT) was 0.69(0.09) in PD and 0.78(0.13) in HV [P < 0.001]. Social cognition indices were not associated with QoL in PD. Clinical parameters—age, gender, HAM‐D, MOCA, education, levodopa equivalent daily dose of medication, number of PD drugs and trihexyphenidyl use did not predict social cognition. Conclusion PD patients were less successful than age, gender matched controls in understanding social situations and other's thought processes and had higher tendency to attribute undesirable events to external causes. Deficits in social cognition did not impair the quality of life.

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Social Cognition and Cognitive Decline in Patients with Parkinson’s Disease

Cited by 23 publications

References 78 publications

What Do We Know about Theory of Mind Impairment in Parkinson’s Disease?

What Do We Know about Theory of Mind Impairment in Parkinson’s Disease?

The Impact of Parkinson’s Disease on Social Communication: An Exploratory Questionnaire Study

Social Cognition in Parkinson's Disease: A Case‐Control Study

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