Social cognitive impairments in first episode psychosis

Bertrand, Marie-Claude; Sutton, H. Eldon; Achim, Amélie M.; Malla, Ashok; Lepage, Martín

doi:10.1016/j.schres.2007.05.033

Cited by 115 publications

(76 citation statements)

References 47 publications

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“…There is also growing awareness that social cognition is a unique and important neurocognitive domain for human social function (Shultz and Dunbar, 2012). Social cognitive deficits, including emotion recognition, predict social function in both early psychosis and autism above other tests of neurocognition (Bertrand et al, 2007;Losh et al, 2009). Thus, enhancement of the ability to recognize emotion in faces has the potential to improve social functioning in healthy humans and across clinical disorders.…”

Section: Introductionmentioning

confidence: 99%

The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis

Shahrestani

Kemp

Guastella

2013

Neuropsychopharmacol

265

183

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Many studies have highlighted the potential of oxytocin (OT) to enhance facial affect recognition in healthy humans. However, inconsistencies have emerged with regard to the influence of OT on the recognition of specific emotional expressions (happy, angry, fear, surprise, disgust, and sadness). In this study, we conducted a meta-analysis of seven studies comprising 381 research participants (71 females) examining responses to the basic emotion types to assess whether OT enhances the recognition of emotion from human faces and whether this was influenced by the emotion expression and exposure time of the face. Results showed that intranasal OT administration enhances emotion recognition of faces overall, with a Hedges g effect size of 0.29. When analysis was restricted to facial expression types, significant effects of OT on recognition accuracy were specifically found for the recognition of happy and fear faces. We also found that effect sizes increased to moderate when exposure time of the photograph was restricted to early phase recognition (o300 ms) for happy and angry faces, or later phase recognition for fear faces (4300 ms). The results of the meta-analysis further suggest that OT has potential as a treatment to improve the recognition of emotion in faces, allowing individuals to improve their insight into the intentions, desires, and mental states of others.

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Section: Introductionmentioning

confidence: 99%

The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis

Shahrestani

Kemp

Guastella

2013

Neuropsychopharmacol

265

183

View full text Add to dashboard Cite

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“…Similar results have been reported previously (Sprong, et al, 2007, Bora, et al, 2009). Since their first description as hallmark features in schizophrenia (Frith, 1992), mentalizing deficits can be found in the acute and remitted phase of the disorder (Inoue et al, 2006, Mo et al, 2008 , in first episode psychosis (Bertrand et al, 2007), schizotypy (Pickup, 2006) and in relatives of schizophrenia patients (Janssen et al, 2003). …”

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confidence: 99%

Sense of agency and mentalizing: Dissociation of subdomains of social cognition in patients with schizophrenia

Schimansky

David

Rössler

et al. 2010

Psychiatry Research

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The sense of agency, i.e., the sense that "I am the one who is causing an action", and mentalizing, the ability to understand the mental states of other individuals, are key domains of social cognition. It has been hypothesized that an intact sense of agency is an important precondition for higher-level mentalizing abilities. A substantial body of evidence shows that both processes rely on similar brain areas and are severely impaired in schizophrenia, suggesting a close link between agency and mentalizing. Yet this relationship has not been explicitly tested. We investigated 40 individuals with schizophrenia and 40 healthy controls on an agency and mentalizing task. On the agency task, participants carried out simple mouse movements and judged the partially manipulated visual feedback as either self-or other-generated. On the mentalizing task, participants inferred mental states from pictures that depicted others' eyes ("Reading the mind in the eyes test"). Neuropsychological, psychopathological and social functioning levels were also evaluated. Both sense of agency and mentalizing were impaired in schizophrenia patients compared to healthy controls. However, testing for a relationship revealed no significant correlations between the two processes, either in the schizophrenia or the control group. The present findings demonstrate a dissociation of agency and mentalizing deficits in schizophrenia, suggesting that the multifaceted construct of social cognition consists of independent subdomains in healthy and psychiatrically ill individuals. AbstractThe sense of agency, i.e., the sense that "I am the one who is causing an action", and mentalizing, the ability to understand the mental states of other individuals, are key domains of social cognition. It has been hypothesized that an intact sense of agency is an important precondition for higher-level mentalizing abilities. A substantial body of evidence shows that both processes rely on similar brain areas and are severely impaired in schizophrenia, suggesting a close link between agency andmentalizing. Yet this relationship has not been explicitly tested. We investigated 40 individuals with schizophrenia and 40 healthy controls on an agency and mentalizing task. On the agency task, participants carried out simple mouse movements and judged the partially manipulated visual feedback as either self or other generated. On the mentalizing task, participants inferred mental states from pictures that depicted others' eyes ("Reading the Mind in the Eyes test"). Neuropsychological, psychopathological and social functioning levels were also evaluated.Both sense of agency and mentalizing were impaired in schizophrenics compared to healthy controls.However, testing for a relationship revealed no significant correlations between the two processes, either in the schizophrenia or the control group.The present findings demonstrate a dissociation of agency and mentalizing deficits in schizophrenia,suggesting that the multifaceted construct of social cognition consists of independ...

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“…Given that clients most frequently request help with social and vocational functioning, programs should consider incorporating (or expanding) supported employment and education components. To address the frequent social functioning requests, future research should examine the effectiveness and feasibility of implementing interventions aimed to improve social cognition in this population (Bertrand et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Essential components of early intervention programs for psychosis: Available intervention services in the United States

White

Luther

Bonfils

et al. 2015

Schizophrenia Research

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Programs providing interventions for early psychosis are becoming commonplace in the United States (U.S.); however, the characteristics of existing services remain undocumented. We examined program characteristics, clinical services, and program eligibility criteria for outpatient early intervention programs across the U.S. using a semistructured telephone interview. Content analysis was used to identify the presence or absence of program components, based in part on a recent list of essential evidence-based components recommended for early intervention programs (Addington, MacKenzie, Norman, Wang and Bond, 2013) as well as program characteristics, including eligibility criteria. A total of 34 eligible programs were identified; 31 (91.2%) program representatives agreed to be interviewed. Of the examined components, the most prevalent were individual psychoeducation and outcomes tracking; the least prevalent were outreach services and communication with inpatient units. The populations served by US programs were most frequently defined by restrictions on the duration of psychosis and age. This study provides critical feedback on services for the early psychosis population and identifies research to practice gaps and areas for future improvement.

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Social cognitive impairments in first episode psychosis

Cited by 115 publications

References 47 publications

The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis

The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis

Sense of agency and mentalizing: Dissociation of subdomains of social cognition in patients with schizophrenia

Essential components of early intervention programs for psychosis: Available intervention services in the United States

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