Social exclusion modulates event-related frontal theta and tracks ostracism distress in children

Noordt, Stefon van; White, Lars O.; Wu, Jia; Mayes, Linda C.; Crowley, Michael J.

doi:10.1016/j.neuroimage.2015.05.085

Cited by 42 publications

(45 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As such, additional research is need to identify ERPs that may be sensitive to participants voting to reject vs. accept peers, as well as those that may me modulated by anticipation of feedback from more or less desirable peers and/or the possibility of acceptance or rejection. Lastly, analytical approaches such as time frequency analyses (van der Molen et al, 2016; van Noordt, White, Wu, Mayes, & Crowley, 2015), should be considered in future work in order to further inform understanding of neurophysiological measures of social processing.…”

Section: Discussionmentioning

confidence: 99%

Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures

Kujawa

Kessel

Carroll

et al. 2017

Biological Psychology

View full text Add to dashboard Cite

Peer relationships play a major role in adolescent development, but few methods exist for measuring social processing at the neurophysiological level. This study extends our pilot study of Island Getaway, a task for eliciting event-related potentials (ERPs) to peer feedback. We differentiated ERPs using principal components analysis (PCA) and examined associations with behavioral and self-report measures in young adolescents (N = 412). PCA revealed an early negativity in the ERP enhanced for rejection feedback, followed by a series of positivities (consistent with reward positivity [RewP], P300, and late positive potential) that were enhanced for acceptance feedback. Greater self-reported task engagement correlated with a larger RewP to acceptance and lower rates of rejecting peers. Youth higher in depressive symptoms exhibited a blunted RewP to social acceptance and reported lower engagement. Results highlight ERP components sensitive to peer feedback that may inform understanding of social processes relevant to typical and atypical development.

show abstract

Section: Discussionmentioning

confidence: 99%

Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures

Kujawa

Kessel

Carroll

et al. 2017

Biological Psychology

View full text Add to dashboard Cite

show abstract

“…Neural oscillations are thought to play a key role in processing neural information, and different types of oscillatory activities are being studied for their functions. Exclusion-induced changes in neural oscillations such as alpha and theta frequency bands have also been reported in these areas [39][40][41].…”

Section: Introductionmentioning

confidence: 86%

Effects of Rifaximin on Central Responses to Social Stress—a Pilot Experiment

2018

View full text Add to dashboard Cite

Probiotics that promote the gut microbiota have been reported to reduce stress responses, and improve memory and mood. Whether and how antibiotics that eliminate or inhibit pathogenic and commensal gut bacteria also affect central nervous system functions in humans is so far unknown. In a double-blinded randomized study, 16 healthy volunteers (27.00 ± 1.60 years; 9 males) received either rifaximin (600 mg/day) (a poorly absorbable antibiotic) or placebo for 7 days. Before and after the drug intervention, brain activities during rest and during a social stressor inducing feelings of exclusion (Cyberball game) were measured using magnetoencephalography. Social exclusion significantly affected (p < 0.001) mood and increased exclusion perception. Magnetoencephalography showed brain regions with higher activations during exclusion as compared to inclusion, in different frequency bands. Seven days of rifaximin increased prefrontal and right cingulate alpha power during resting state. Low beta power showed an interaction of intervention (rifaximin, placebo) × condition (inclusion, exclusion) during the Cyberball game in the bilateral prefrontal and left anterior cingulate cortex. Only in the rifaximin group, a decrease (p = 0.004) in power was seen comparing exclusion to inclusion; the reduced beta-1 power was negatively correlated with a change in the subjective exclusion perception score. Social stress affecting brain functioning in a specific manner is modulated by rifaximin. Contrary to our hypothesis that antibiotics have advert effects on mood, the antibiotic exhibited stress-reducing effects similar to reported effects of probiotics (supported by NeuroGUT, a EU 7th Framework Programme ITN no. 607652; ClinicalTrials.gov identifier number NCT02793193).

show abstract

“…Offline, the EEG recordings from each of the tasks were merged together and submitted to an automated preprocessing pipeline using EEGLAB (Delorme & Makeig, ) with custom in‐house code created in MATLAB 2010b and executed in Octave 3.6.3 on the Shared Hierarchical Academic Research Computing Network (SHARCNet, http://www.sharcnet.ca). Specifically, the data were systematically processed to identify and remove bad channels and periods of nonstationarity on the basis of correlation distributions between neighboring channels (see Desjardins & Segalowitz, ; van Noordt, Desjardins, & Segalowitz, ; van Noordt, White, Wu, Mayes, & Crowley, , for an expanded description of these methods). There was an average of 19 channels ( SD = 7.97, ranging from 3–37) removed before submitting the data to independent component analysis (ICA).…”

Section: Methodsmentioning

confidence: 99%

A functional classification of medial frontal negativity ERPs: Theta oscillations and single subject effects

2016

Self Cite

View full text Add to dashboard Cite

Theta oscillations in the EEG have been linked to several ERPs that are elicited during performance-monitoring tasks, including the error-related negativity (ERN), no-go N2, and the feedback-related negativity (FRN). We used a novel paradigm to isolate independent components (ICs) in single subjects' (n = 27) EEG accounting for a medial frontal negativity (MFN) to response cue stimuli that signal a potential change in future response demands. Medial frontal projecting ICs that were sensitive to these response cues also described the ERNs, no-go N2s, and, to a lesser extent, the FRNs, that were elicited in letter flanker, go/no-go, and time-estimation tasks, respectively. In addition, percentile bootstrap tests using trimmed means indicated that the medial frontal ICs show an increase in theta activity during the ERN, no-go N2, and FRN across tasks and within individuals. Our results provide an important validation of previous studies by showing that increases in medial frontal theta to cognitively challenging events in multiple paradigms is a reliable effect within individuals and can be elicited by basic stimulus cues that signal the potential need to adjust response control. Thus, medial frontal theta reflects a neural response common to all MFN paradigms and characterizes the general process of controlling attention without the need to induce error commission, inhibited responses, or to present negative feedback.

show abstract

Social exclusion modulates event-related frontal theta and tracks ostracism distress in children

Cited by 42 publications

References 66 publications

Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures

Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures

Effects of Rifaximin on Central Responses to Social Stress—a Pilot Experiment

A functional classification of medial frontal negativity ERPs: Theta oscillations and single subject effects

Contact Info

Product

Resources

About