2023
DOI: 10.1101/2023.11.02.23297985
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Social health and subsequent cognitive functioning in people aged 50 years and above: examining the mediating roles of depressive symptoms and inflammatory biomarkers

Jean Stafford,
Serhiy Dekhtyar,
Anna-Karin Welmer
et al.

Abstract: BackgroundSocial health markers, including marital status, contact frequency, network size, and social support, have shown associations with cognition. However, the underlying mechanisms remain poorly understood. We investigated whether depressive symptoms and inflammation mediated associations between social health and subsequent cognition.MethodsIn the English Longitudinal Study of Ageing (ELSA; n=7,136; aged 50+), we used four-way decomposition to examine to what extent depressive symptoms, C-reactive prote… Show more

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