Social jetlag, a novel predictor for high cardiovascular risk in blue‐collar workers following permanent atypical work schedules

Madeira, Sara Alexandra Gamboa; Reis, Cátia; Paiva, Teresa; Moreira, C.; Nogueira, Paulo; Roenneberg, Till

doi:10.1111/jsr.13380

Cited by 23 publications

(9 citation statements)

References 35 publications

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“…When analyzing social classes, we found a higher risk of obesity, diabetes, hypertension, MetS, atherogenic index, CVR, and BARD scoring system in blue-collar compared to white-collar workers. These results are consistent with other published studies that found that shift work is associated with an increased risk of CVD [ 55 ]. Socioeconomic and demographic differences are associated with an uneven distribution of health [ 56 ], in such a way that socioeconomic level presents an inverse association with the prevalence of MetS and diabetes mellitus, with a worse health status in the population with less purchasing power [ 57 ].…”

Section: Discussionsupporting

confidence: 94%

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

et al. 2022

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Background Aging of the world population is one of the most significant demographic changes of our time. Populations older than 60 years are heterogeneous, and age is an independent cardiovascular risk factor aggravated by frailty, obesity, and diabetes, and influenced by several factors, including sex and socioeconomic status. The objective of this study was to calculate cardiovascular risk in workers of both sexes over 60 years of age and to assess whether there are difference s by sex, social class, smoking, and type of job. Methods A cross-sectional study was carried out in 15,057 elderly Spanish workers from different autonomous communities in Spain and with different labor occupations. Anthropometric, sociodemographic, clinical, and laboratory values were determined. People were classified according to age from 60 to 64 years inclusive and from 65 to 69 years, smokers and non-smokers, and both blue-collar and white-collar workers. Subsequently, a multivariate analysis was carried out. Results Men, blue-collar workers, smokers, and aging were factors that influenced cardiovascular risk: with an OR of 3.27 (95% CI: 2.64–4.05) in people 65 years of age or older versus the younger group, and an OR of 3.15 (95% CI: 2.69–3.69) in smokers versus non-smokers. A stronger independent association was found between smoking, age, and cardiovascular risk. The risk of developing non-alcoholic fatty liver and liver fibrosis was much higher in men than in women, with an OR of 4.06 (95% CI: 3.66–4.50) for the former and an OR of 2.10 (95% CI: 1.95–2.26) for the BARD index. Conclusions The highest risk groups were observed in male subjects with a history of smoking and blue-collar workers and, as such, should be considered for cardiovascular risk screening programs.

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Section: Discussionsupporting

confidence: 94%

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

et al. 2022

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“…Our body clocks systematically adjust to changes in photoperiod, but by suddenly changing the social clocks by one hour we abruptly change the phase angle between the time of arising and dawn [ 18 ]. Even without a change in time of arising caused by DST, many individuals experience circadian misalignment coupled with sleep loss [ 15 , 19 , 20 ], which has been associated with an increase in the risk of cardiovascular diseases [ 21 , 22 ]. Superimposed abrupt circadian misalignment caused by the spring DST transition might therefore pose additional cardiovascular burden on individuals with high levels of social jetlag, in primarily late chronotypes.…”

Section: Circadian Clock Chronotypes and Dstmentioning

confidence: 99%

Acute Myocardial Infarction and Daylight Saving Time Transitions: Is There a Risk?

Čulić

Kantermann

2021

Clocks & Sleep

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Available evidence on the risk of acute myocardial infarction (AMI) in the days after the spring daylight saving time (DST) transition suggests either a modest increase or no risk increase. Partial sleep deprivation and enhanced circadian clock misalignment have been implicated as the underlying mechanisms for increased AMI risk, probably via enhanced thrombo-inflammatory processes and activation of the sympathetic nervous system. Most of the studies, as we suggest as a perspective here, have used potentially inappropriate control periods, including the two post-transitional weeks, because adjustment after the spring DST transition lasts at least four weeks for all chronotypes and probably even beyond this period for late chronotypes. The most plausible conclusions, at the moment, for the risk of AMI after the spring DST transition are: (1) the risk is increased, (2) a relatively modest risk increase could be currently underestimated or in some studies undetected, (3) late chronotypes and/or individuals with high levels of social jetlag (a proxy for circadian clock misalignment) could be more affected by the phenomenon, and (4) underlying pathophysiological mechanisms should be further explored. As a significant part of world’s population continues to be affected by the biannual clock change, the question of increased AMI risk in the post-transitional period remains an intriguing public health issue.

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“…Another form of chronic circadian misalignment is known as social jetlag, which is characterized by an ongoing discrepancy of an individual's sleep/wake cycle between workdays and free days. Importantly, several health consequences, including mood disorders, cardiac disease, obesity, metabolic syndrome, and type 2 diabetes mellitus, have been strongly linked to social jetlag ( Gamboa Madeira et al , 2021 ; Islam et al , 2020 ; Koopman et al , 2017 ; Roenneberg et al , 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Different levels of circadian (de)synchrony – where does it hurt?

et al. 2023

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A network of cellular timers ensures the maintenance of homeostasis by temporal modulation of physiological processes across the day. These so-called circadian clocks are synchronized to geophysical time by external time cues (or zeitgebers). In modern societies, natural environmental cycles are disrupted by artificial lighting, around-the-clock availability of food or shift work. Such contradictory zeitgeber input promotes chronodisruption, i.e., the perturbation of internal circadian rhythms, resulting in adverse health outcomes. While this phenomenon is well described, it is still poorly understood at which level of organization perturbed rhythms impact on health and wellbeing. In this review, we discuss different levels of chronodisruption and what is known about their health effects. We summarize the results of disrupted phase coherence between external and internal time vs. misalignment of tissue clocks amongst each other, i.e., internal desynchrony. Last, phase incoherence can also occur at the tissue level itself. Here, alterations in phase coordination can emerge between cellular clocks of the same tissue or between different clock genes within the single cell. A better understanding of the mechanisms of circadian misalignment and its effects on physiology will help to find effective tools to prevent or treat disorders arising from modern-day chronodisruptive environments.

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Social jetlag, a novel predictor for high cardiovascular risk in blue‐collar workers following permanent atypical work schedules

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 23 publications

References 35 publications

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

Acute Myocardial Infarction and Daylight Saving Time Transitions: Is There a Risk?

Different levels of circadian (de)synchrony – where does it hurt?

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Social jetlag, a novel predictor for high cardiovascular risk in blue‐collar workers following permanent atypical work schedules

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 23 publications

References 35 publications

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

Cardiometabolic profile of 15057 elderly Spanish workers: association of sociodemographic variables and tobacco consumption

Acute Myocardial Infarction and Daylight Saving Time Transitions: Is There a Risk?

Different levels of circadian (de)synchrony ­– where does it hurt?

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Product

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Different levels of circadian (de)synchrony – where does it hurt?