PurposeThe purpose of this study is to provide a systematic review of the existing literature on social media (SM) use and examine its relationship with various facets of social well-being (SWB).Design/methodology/approachThe study identifies and selects relevant articles using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework, wherein 273 articles were identified using the keyword search criteria from 5 databases namely Web of Science, Emerald, Pubmed, Google Scholar and EBSCOhost, and finally, 20 relevant studies were included for this systematic review. In order to provide directions for future research, a thorough profile with the key findings and knowledge gaps is presented.FindingsThe majority of the reviewed studies report an increase in the use of SM, especially amongst adolescents, and this suggests a seriously detrimental impact on their SWB in terms of cyberbullying, lifestyle comparison and impact on self-esteem, substance abuse, declined academic performance, fear of missing out (FoMo) and social overload. However, some of the studies reported life satisfaction, a reduction in loneliness and improved social support and belongingness, particularly those focussing on old age people who experience social isolation. The review also affirmed improved job performance and employees’ well-being. These findings vary across various demographic variables and various SM platforms namely Facebook, Twitter, Instagram, WhatsApp, WeChat, YouTube, etc.Originality/valueThe findings have significant implications for SM researchers, family members and educators concerning promoting appropriate SM use, especially in terms of their SWB. The study also provides various suggestions for future studies and the need to further explore the topic as the field of SM use and SWB is ever-growing.