Social neuroscience and mechanisms of risk for mental disorders

Meyer‐Lindenberg, Andreas

doi:10.1002/wps.20121

Cited by 25 publications

(20 citation statements)

References 14 publications

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“…Dimensional approaches to psychiatric therapies have increasingly been supported; to this purpose, Buckholtz and Meyer-Lindenberg have recently proposed a dimensional transdiagnostic “common symptom, common circuit” model of psychopathology suggesting that specific clusters of psychic disturbances correspond to specific clusters of brain network alterations associated with tinnitus perception [63, 141]. We find reliability and promise in this kind of approach in order to diagnose and treat psychiatric comorbidities of tinnitus.…”

Section: Discussionmentioning

confidence: 88%

A Brain Centred View of Psychiatric Comorbidity in Tinnitus: From Otology to Hodology

et al. 2014

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Introduction. Comorbid psychiatric disorders are frequent among patients affected by tinnitus. There are mutual clinical influences between tinnitus and psychiatric disorders, as well as neurobiological relations based on partially overlapping hodological and neuroplastic phenomena. The aim of the present paper is to review the evidence of alterations in brain networks underlying tinnitus physiopathology and to discuss them in light of the current knowledge of the neurobiology of psychiatric disorders. Methods. Relevant literature was identified through a search on Medline and PubMed; search terms included tinnitus, brain, plasticity, cortex, network, and pathways. Results. Tinnitus phenomenon results from systemic-neurootological triggers followed by neuronal remapping within several auditory and nonauditory pathways. Plastic reorganization and white matter alterations within limbic system, arcuate fasciculus, insula, salience network, dorsolateral prefrontal cortex, auditory pathways, ffrontocortical, and thalamocortical networks are discussed. Discussion. Several overlapping brain network alterations do exist between tinnitus and psychiatric disorders. Tinnitus, initially related to a clinicoanatomical approach based on a cortical localizationism, could be better explained by an holistic or associationist approach considering psychic functions and tinnitus as emergent properties of partially overlapping large-scale neural networks.

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Section: Discussionmentioning

confidence: 88%

A Brain Centred View of Psychiatric Comorbidity in Tinnitus: From Otology to Hodology

et al. 2014

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“… 78–83 While previous research has reported neural social stress sensitivity is elevated in individuals exposed to urban environments, 78 , 83 our findings suggest, for the first time, that momentary sensitivity to neighbourhoods subjectively appraised as stressful is associated with more intense psychotic experiences. Geographical momentary assessment studies that allow for real-time tracking and linkage of neighbourhood surroundings with subjective ratings of these 84 , 85 are now needed to elucidate further the interplay of psychological mechanisms and area-level socio-environmental exposures. Similarly, the finding that elevated sensitivity to outsider status is associated with psychotic experiences, though in line with previous research, 34 needs to be further validated in the context of socio-environmental factors that may increase sensitivity to this form of social stress.…”

Section: Discussionmentioning

confidence: 99%

Stress Sensitivity, Aberrant Salience, and Threat Anticipation in Early Psychosis: An Experience Sampling Study

Reininghaus

Kempton

Valmaggia

et al. 2016

SCHBUL

259

243

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While contemporary models of psychosis have proposed a number of putative psychological mechanisms, how these impact on individuals to increase intensity of psychotic experiences in real life, outside the research laboratory, remains unclear. We aimed to investigate whether elevated stress sensitivity, experiences of aberrant novelty and salience, and enhanced anticipation of threat contribute to the development of psychotic experiences in daily life. We used the experience sampling method (ESM) to assess stress, negative affect, aberrant salience, threat anticipation, and psychotic experiences in 51 individuals with first-episode psychosis (FEP), 46 individuals with an at-risk mental state (ARMS) for psychosis, and 53 controls with no personal or family history of psychosis. Linear mixed models were used to account for the multilevel structure of ESM data. In all 3 groups, elevated stress sensitivity, aberrant salience, and enhanced threat anticipation were associated with an increased intensity of psychotic experiences. However, elevated sensitivity to minor stressful events (χ2 = 6.3, P = 0.044), activities (χ2 = 6.7, P = 0.036), and areas (χ2 = 9.4, P = 0.009) and enhanced threat anticipation (χ2 = 9.3, P = 0.009) were associated with more intense psychotic experiences in FEP individuals than controls. Sensitivity to outsider status (χ2 = 5.7, P = 0.058) and aberrantly salient experiences (χ2 = 12.3, P = 0.002) were more strongly associated with psychotic experiences in ARMS individuals than controls. Our findings suggest that stress sensitivity, aberrant salience, and threat anticipation are important psychological processes in the development of psychotic experiences in daily life in the early stages of the disorder.

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“…[6][7][8] Mental health is deeply impacted by interactions between physiological, psychological, behavioral, socioeconomic, environmental, genetic, and epigenetic conditions. 9 In many instances, the contextual factors may outweigh the influence of intrapersonal attributes to determine mental health status among the individuals. 4,9 Several studies suggest that the lived experience in a given environment influences how individuals perceive and respond to the psychological stressors, which involve complex psychopathological processes leading to mental health outcomes.…”

Section: Introductionmentioning

confidence: 99%

“…9 In many instances, the contextual factors may outweigh the influence of intrapersonal attributes to determine mental health status among the individuals. 4,9 Several studies suggest that the lived experience in a given environment influences how individuals perceive and respond to the psychological stressors, which involve complex psychopathological processes leading to mental health outcomes. 10 In this discourse, a growing body of research highlights that the natural environment can positively influence mental health outcomes among individuals and populations.…”

Section: Introductionmentioning

confidence: 99%

Effects of natural environment on mental health: an umbrella review of systematic reviews and meta-analyses

Hossain¹,

Sultana²,

Ma³

et al. 2020

Preprint

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Objectives: To synthesize the evidence on the effects of exposure to natural environment on mental health to inform future policymaking, practice, and research. Methods: A systematic search of nine major databases and additional sources were conducted using relevant keywords for the natural environment and mental health till November 2019. We included systematic reviews or meta-analyses reporting any measures of associations between the natural environment and mental health. The data on study characteristics and research findings were extracted using the JBI data extraction tool and synthesized narratively.Results: Twenty reviews were included in this umbrella review reporting both correlational and experimental studies. Among diverse population groups, the exposure to the natural environment was associated with improvements in depressive symptoms, anxiety, mood disorders, stress, cognitive and emotional functions, affect, happiness, and overall mental wellbeing. Conclusions: The findings of this review inform beneficial mental health outcomes associated with exposure to the natural environment. This umbrella review suggests collaborative policymaking, advanced research, and evidence-based practice protecting the natural environment and improving mental health across populations.

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Social neuroscience and mechanisms of risk for mental disorders

Cited by 25 publications

References 14 publications

A Brain Centred View of Psychiatric Comorbidity in Tinnitus: From Otology to Hodology

A Brain Centred View of Psychiatric Comorbidity in Tinnitus: From Otology to Hodology

Stress Sensitivity, Aberrant Salience, and Threat Anticipation in Early Psychosis: An Experience Sampling Study

Effects of natural environment on mental health: an umbrella review of systematic reviews and meta-analyses

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