The 24-item Social Provision Scale is among the most frequently used self-report scales to assess perceived social support. A shortened 10-item version (SPS-10) with promising psychometric properties has been proposed. However, so far only a few studies in specific cultural contexts investigated its psychometric properties. Thus, the aim of the current study was an extensive investigation of the psychometric properties of the SPS-10 among 38 countries ( N = 88,857 respondents) using the COVIDiSTRESS Global Survey data. Item response theory bifactor analysis revealed that the general factor accounts for the largest part of the covariance among the items in all countries (explained common variance ≥ .75) and that the mean/sum score of the SPS-10 can be used as a total score of perceived general social support. Reliability was high for all countries (ρunidimensional GRM ≥ .89). Measurement invariance and differential item/test functioning analysis of the unidimensional graded response model indicated negligible differential test functioning across countries. The association with the external criteria mainly supported its construct validity. The SPS-10 is a psychometrically sound measure of perceived social support for large-scale cross-cultural studies.