Social support, stigma, and the mediating roles of depression on self-reported medication adherence of HAART recipients in China

Man, Jiang; Yang, Jiezhe; Yang, Song; Zheng, Jinlei; Li, Xinghui; Yang, Guang; Ma, Yong; Xu, Peng; Zhang, Ziqi; Pan, Xiaohong; Wang, Ying

doi:10.1080/09540121.2019.1587360

Cited by 12 publications

(11 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The observed prevalence of depressive symptoms (37.9%) is higher than the general older population, 26 indicating additional mental health burden among older men living with HIV/AIDS in Chongqing. Although the observed depression prevalence in our study is lower than that observed in studies conducted in China’s other cities such as Nanning, 16 Wuhan, 27 it is higher than that in Nanjing, 28 Sichuan 29 and similar to Shanghai 30 and Guangzhou, 31 potentially due to the variations in the employment of depression assessment tools. We used the Zung Self-Rating Depression Scale (SDS) to measure depressive symptoms, while others have used the Beck Depression Inventory (BDI), the Geriatric Depression Scale (GDS), and Patient Health Questionnaire (PHQ).…”

Section: Discussioncontrasting

confidence: 91%

Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China

Tan¹,

Zhou²,

Lu³

et al. 2022

JMDH

View full text Add to dashboard Cite

Purpose This study aimed to assess the proportion of depression and its associated factors among men living with HIV/AIDS and aged 50 and over in Chongqing, China. Methods This cross-sectional study included 774 men diagnosed as HIV/AIDS and aged 50 and over in four regions. Data were collected through face-to-face interviews with a structured questionnaire. Multivariate logistic regression analysis was performed to identify factors associated with depression. A two-tailed P -value less than 0.05 was considered as statistical significance. Results A total of 293 participants (37.9%) reported depressive symptoms. Results from multivariate logistic regression suggested that individuals aged ≥70 (AOR = 1.99, 95% CI: 1.28–3.08) and those living in rural areas (AOR = 2.79, 95% CI: 1.96–3.97) were associated with higher odds of depression, while those being employed (AOR = 0.50, 95% CI: 0.32–0.80) and with monthly income >3000 CNY (AOR = 0.47, 95% CI: 0.30–3.74) had lower odds of depression. Conclusion Our findings indicate a high prevalence of depression among older men living with HIV/AIDS in Chongqing, China. Age, residence, employment, and income have been identified as potential risk factors of depressive symptoms. Mental-health intervention initiatives should be tailored to target adults with a higher risk of depression.

show abstract

Section: Discussioncontrasting

confidence: 91%

Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China

Tan¹,

Zhou²,

Lu³

et al. 2022

JMDH

View full text Add to dashboard Cite

show abstract

“…These results are consistent with those from previous studies in other countries [6,25,26]. Thus, it is important to improve depression symptoms, mental health, and recover from drug dependence to increase ART adherence.…”

Section: Relationship Of Adherence and Adherence-related Factorssupporting

confidence: 92%

A web-based survey finds low antiretroviral therapy adherence in approximately 35% of Japanese people living with HIV

Inoue¹,

Oka

Yokoyama

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: Long-term medical care for people living with HIV/AIDS (PLHIV) is critical for treatment efficacy, and various studies have examined causes of antiretroviral therapy (ART) non-adherence. Physicians are assuming that patients are maintaining high adherence. However, little is known about situation of the real-world adherence. Methods: We conducted an anonymous self-administered web-based survey that asking their adherence for a total of 1,030 Japanese PLHIV who were currently on ART. The adherence was judged in terms of the 8-item Morisky Medication Adherence Scale (MMAS-8). Data were analysed based on patient-related factors, therapy-related factors, condition-related factors, and healthcare team/system-related factors.Results: A total of 821 PLHIV responded to the survey were analysed further. Among them, 291 responders (35%) were identified as being in the low adherence group. The study showed a statistically significant relationship between the number of missed anti-HIV drug doses within the previous 2-week and the long-term adherence by the MMAS -8 score. Risk factors for low adherence included age (younger than 21 years), moderate to severe depression, and drug dependence. Adherence was also influenced by the shared decision-making process, including treatment selection, doctor-patient relations, and treatment satisfaction.Conclusions: A web-based survey found low ART adherence in approximately 35% of Japanese PLHIV. The adherence was mainly affected by factors for treatment decision. A medical team support is critical to improve adherence.

show abstract

“…Though the relationship between disclosure and social support may be complex, social support, or more importantly the lack thereof, is often negatively associated with a range of psychosocial outcomes including distress and stigma, as well as clinical outcomes such as medication adherence [ 8 , 55 ]. One study from Ethiopia found that the relationship between social support and psychological distress was confounded by high levels of enacted stigma [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

“…Another study in the USA found that depressive symptoms mediated the association between social support and HIV disclosure for women. However, among men, social support was associated with depressive symptoms, but not disclosure practices [ 55 , 56 ]. While social support was not measured directly in the cohort, marital status may serve as a proxy for social support in this setting, as approximately half of the cohort was married, and a spouse was the person most often disclosed to.…”

Section: Discussionmentioning

confidence: 99%

Psychological Distress Increases 30-Fold Among People with HIV in the First Year on ART in Nigeria—a Call for Integrated Mental Health Services

et al. 2022

View full text Add to dashboard Cite

Background Few studies have longitudinally assessed psychological distress among people with HIV (PWH) initiating ART in resource-limited settings. Method Baseline, 6-month, and 12-month psychological distress were measured in a Nigerian cohort newly initiating therapy; the relationship between baseline factors and psychological distress at 12 months was assessed; and the association between psychological distress at 12 months and care retention or immunologic failure was determined. Results Among 563 patients, median age was 38 years (IQR: 33–46 years), 62% were female, and 51% were married. Psychological distress increased from 3% at baseline to 34% at 12 months. Age (aOR 1.28, 95% CI 1.06–1.56), female sex (aOR 2.89, 95% CI 1.93–4.33), lack of disclosure (aOR 4.32, 95% CI 2.48–7.51), and time on ART (6 months [aOR 6.91, 95% CI 3.14–15.18] and 12 months [aOR 32.63, 95% CI 16.54–64.36]) were associated with psychological distress while being married (OR 0.42, 95% CI 0.30–0.61) was associated with reduced odds. Tweve-month psychological distress was associated with increased risk of immunologic failure (aOR 2.22, 95% CI 1.31–3.82). Conclusion The risk of psychological distress increased 30-fold in the first year on therapy in PWH in Nigeria. Supplementary Information The online version contains supplementary material available at 10.1007/s12529-022-10068-8.

show abstract

Social support, stigma, and the mediating roles of depression on self-reported medication adherence of HAART recipients in China

Cited by 12 publications

References 64 publications

Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China

Depression and Associated Factors Among Men Living with HIV/AIDS Aged 50 Years and Over in Chongqing, China

A web-based survey finds low antiretroviral therapy adherence in approximately 35% of Japanese people living with HIV

Psychological Distress Increases 30-Fold Among People with HIV in the First Year on ART in Nigeria—a Call for Integrated Mental Health Services

Contact Info

Product

Resources

About