Socioeconomic Factors and the Risk of Anencephaly in a Mexican Population: A Case-Control Study

Muñoz, Julia Blanco; Lacasaña, Marina; Aburto, Victor Hugo Borja; Sánchez, Luisa Elvira Torres; García, Ana M.; Carrillo, Luis Rodolfo García

doi:10.1177/003335490512000108

Cited by 30 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our finding of an association between low levels of maternal education and an increased risk of NTDs is consistent with the conclusions of Wasserman et al 9 . Their results have been substantiated by several subsequent studies, where the reported risk estimates for NTDs ranged between 1.8 and 2.3 for mothers with less than a high school education 4,5,10 . These findings, however, diverge from the conclusions of two other studies that observed no association between risk of NTDs and educational level of the mother 11,12 …”

Section: Discussionsupporting

confidence: 90%

“…Two of the other studies were conducted in Colorado 10 and Texas, 20 respectively, and limited their study population to Hispanic women who were born either in the US or Mexico, in all cases prior to fortification. Two further studies focused on women who resided in Mexico 4 and Spain 12 respectively. In addition, the studies did not derive the samples of infants with malformations in an equivalent manner – one included all liveborn, stillborn and electively terminated cases with NTDs, 9 another used livebirths and stillbirths, 20 and a third used only livebirths 10 …”

Section: Discussionmentioning

confidence: 99%

“…As early as 1958, several studies in the British Isles showed a two‐ to fourfold increase in the risk of anencephaly and spina bifida among lower socio‐economic groups 1 . The elevated risk associated with lower SES has been observed in several other countries, including Australia, 2 Canada, 3 Mexico 4 and China 5 . In the United States, this association was reported in one of the earliest studies on the prevalence of NTDs 6 .…”

Section: Introductionmentioning

confidence: 85%

See 2 more Smart Citations

Neural tube defects: an analysis of neighbourhood‐ and individual‐level socio‐economic characteristics

Grewal

Carmichael

Song

et al. 2009

Paediatric Perinatal Epid

View full text Add to dashboard Cite

Summary Several studies have reported that neural tube defects (NTD) occur more frequently among children born to women of lower socio-economic status (SES). This study investigated the relationship between individual- and neighbourhood-level SES and the risk of an NTD-affected pregnancy. Data were drawn from a population-based case-control study of fetuses and infants among a cohort of California births between July 1999 and June 2003. Information on individual SES was obtained via telephone interviews with mothers of 337 (76% of eligible) cases and 626 (79% of eligible) non-malformed liveborn controls. Respondents’ addresses were linked to the 2000 US Census to characterise six measures of neighbourhood SES (education, poverty, unemployment, occupation, crowding and rental occupancy). The analyses indicated that relative to women with a high school education, those with less than a high school education had a 1.7-fold increased risk of delivering infants with NTDs [95% CI 1.2, 2.6]. Twofold elevated risks for NTDs were observed for women with less than a high school education who lived in neighbourhoods where a majority of residents had not graduated from high school [95% CI 1.3, 3.1]. No consistent risk gradients were observed between NTD-affected pregnancies and indicators of lower neighbourhood SES. Results for phenotype subgroups were similar to those for all cases. Low maternal education was associated with an elevated risk of NTD in offspring. This risk varied by the education profile of the neighbourhood: women who did not graduate from high school and lived in less educated neighbourhoods exhibited a higher risk.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 85%

See 1 more Smart Citation

Neural tube defects: an analysis of neighbourhood‐ and individual‐level socio‐economic characteristics

Grewal

Carmichael

Song

et al. 2009

Paediatric Perinatal Epid

View full text Add to dashboard Cite

show abstract

“…This finding goes in concordance with other studies where increased incidences of NTD's have been found in families of low SES. Blanco Muñoz et al .,[ 4 ] in their study, in a Mexican population found increased risk of anencephaly in mothers of low SES. Mutchinick et al .…”

Section: Discussionmentioning

confidence: 93%

Epidemiology of the neural tube defects in Kashmir Valley

Laharwal¹,

Sarmast²,

Ramzan³

et al. 2016

Surg Neurol Int

View full text Add to dashboard Cite

Background:Neural tube defects (NTDs) are the most common congenital malformations affecting the brain and spinal cord and have a multifactorial etiology. Genetic and environmental factors have been found to cause these defects, both individually and in combination.Methods:A 2-year hospital-based prospective study was carried out from November 2013 to October 2015 to determine the incidence, types, demographics, risk factors, and other associated anamolies relevant to NTDs in Kashmir Valley. A detailed history of the mother was taken along with detailed clinical examination of neonate including measurement of head circumference and checking the status of fontanella, whether lax/full/bulging/or tense, type of NTD. Investigations that were done included were X-ray skull: Anterior-posterior (AP) and lateral, X-ray spine: AP and lateral, ultrasonography abdomen, magnetic resonance imaging: Spine and brain.Results:The total number of babies with NTD's was 125 with an overall incidence of 0.503. Kupwara district was having the highest incidence (1.047) and Srinagar district the lowest incidence of NTD's (0.197). Majority of NTD's (116 cases, 92.8%) were found in the rural areas. Among the different types of NTD's, spina bifida had an incidence of 0.342 (85 cases, 68%) and anencephaly had an incidence of 0.113 (28 cases, 22.4%). There was a slight preponderance of females over males with NTD's. There were 70 females (56%) and 55 males (44%), respectively, with a male: female ratio of 0.8:1Conclusions:The incidence rates of NTDs is very high for Kashmir Valley. Geographical distribution of NTDs at this place confirms a relationship between the socioeconomic status, educational status, maternal too young or advanced age, and environmental factors for the development of a NTD. The results of this study point to the importance establishing a health policy to prevent NTD in Kashmir Valley.

show abstract

“…Blanco Muñoz et al . [26] in their study in a Mexican population found increased risk of anencephaly in mothers of low SES. Mutchinik et al .…”

Section: Discussionmentioning

confidence: 97%

Epidemiology of the neural tube defects in Kashmir Valley

et al. 2016

View full text Add to dashboard Cite

Introduction/Background:Neural tube defects (NTD) are the most common congenital malformations affecting the brain and spinal cord and have a multifactorial etiology. Genetic and environmental factors have been found to cause these defects, both individually and in combination.Aims and Objectives:The aim of this study was to determine the incidence, types, demographics, risk factors, and other associated anomalies relevant to NTDs in Kashmir Valley.Materials and Methods:A 2-year hospital-based prospective study was carried out from November 2013 to October 2015. A detailed history of the mother was taken along with detailed clinical examination of neonate including measurement of head circumference and checking the status of fontanella, whether - lax/full/bulging/or tense, type of NTD. Investigations that were done included were X-ray skull: Anteroposterior (AP) and lateral, X-ray spine: AP and lateral, ultrasonography abdomen, magnetic resonance imaging: Spine and brain.Results:The total number of babies with NTD's was 125 with an overall incidence of 0.503. District Kupwara was having the highest incidence (1.047) and district Srinagar the lowest incidence of NTD's (0.197). The majority of NTD's (116 cases, 92.8%) were found in the rural areas. Among the different types of NTD's, spina bifida had an incidence of 0.342 (85 cases, 68%), and anencephaly had an incidence of 0.113 (28 cases, 22.4%). There was a slight preponderance of females over males with NTD's. There were70 females (56%) and 55 males (44%) respectively with a male:female ratio of 0.8:1.Conclusions:The incidence rates of NTDs are very high for Kashmir Valley. Geographical distribution of NTDs at this place confirms a relationship between the socioeconomic status, educational status, maternal age and environmental factors for the development of an NTD. The results of this study point to the importance establishing a health policy to prevent NTDs in Kashmir Valley.

show abstract

Socioeconomic Factors and the Risk of Anencephaly in a Mexican Population: A Case-Control Study

Cited by 30 publications

References 24 publications

Neural tube defects: an analysis of neighbourhood‐ and individual‐level socio‐economic characteristics

Neural tube defects: an analysis of neighbourhood‐ and individual‐level socio‐economic characteristics

Epidemiology of the neural tube defects in Kashmir Valley

Epidemiology of the neural tube defects in Kashmir Valley

Contact Info

Product

Resources

About