“…The smoking (17.3% of screened with a 2,786 cig a year; 63.2% of male and 9.1% of female; 70.6% in the trial; a contribution to mortality is about 29%), excessive alcohol consumption (1.8% of screened with a 11.6 L per year mostly of beer and vodka; 50.6% in the trial; about 70% consumed strong alcoholic beverages; responsible for 25.6% of CV deaths in male and 15.4% in female), unhealthy diet with insufficient consumption of fruits, vegetables, sea food, unsaturated fat, and proteins (mean 12% of the daily consumption) with abundance of carbohydrates/ sugar (up to 57% of diet), saturated and trans fats (up to 29-40% of the energy) including palm oil, butterfat, mayonnaise, and junk processed red meat), psychosocial factors (75% of Russians are not adapted to new living conditions, 20%-stress, 11.7%-anxiety, and 9.6%-depression) and physical inactivity (19.6% of screened; at least 73.9% of men and 74.8% of women) remain the major modifiable risk factors. They, in turn, affect (see Figure 3) (5,14,15,(17)(18)(19)(20)(21)(22)(25)(26)(27)(28)(29)(30) such risk factors as dyslipidemia (86.7% in the trial), obesity (16.7% of screened; mean BMI in the trial was 28.4), and hypertension (about 40.8% suffered; 86.1% in the trial), which is relevant to findings of the EUROASPIRE IV trial (31,32) in the European population, and screening studies of the Russian Cardiovasc Diagn Ther 2017;7(1):60-84 cdt.amegroups.com 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 Total mortality per 1,000, 2012…”