Background: Women are underrepresented in acute myocardial infarction (AMI) studies. Furthermore, there is scarce information regarding women with AMI in Latin America.Aims: To describe the presentation, clinical characteristics, risk factor burden, evidencebased care, and in-hospital outcome in a population of women with AMI admitted to a coronary care unit (CCU) in Mexico.Methods: Retrospective cohort study including patients with AMI admitted from January 2006 to December 2021 in a CCU. We identified patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). We described demographic characteristics, clinical variables, treatment, and in-hospital outcomes according to gender. Cox regression analysis was used to identify predictors of mortality. 2 Arias-Mendoza et al.