“…In order to reduce alveolar bone dimensional changes, several techniques aiming at enhancing the regeneration process in the extraction socket have been adopted 72 , such as filling the socket with autogenous bone grafts 12 or bone substitutes 8,10,15,18,28,29,31,64,76 , guided bone regeneration (GBR) with resorbable or non-resorbable barriers 11,13,14,20,43,58 , and the use of various bone promoting molecules such as enamel matrix derivative 20 , recombinant growth and differentiation factors 13,19,35,46,52,53 , and autologous platelet concentrates 3,37,60,65 . These techniques have been used alone or in combinations, in the search for the optimal socket preservation method.…”