Socket Preservation using Human Recombinant Growth Hormone Associated with Bio-Oss Biomaterial with the Purpose of Improving Healing and Reducing Treatment Time - A Case Report

Abstract

The purpose of this article is to describe a clinical case where recombinant human growth hormone (rhGH) associated with Bio-Oss  was used in socket preservation. 53-year-old female patient, ASA I, attended the dental clinic presenting a root fracture of the second upper right premolar. The treatment plan consisted of tooth removal and socket preservation with rhGH and Bio-Oss. After 4 months, a tomography scan was performed before implant placement. At the time of the implant placement, a bone sample was sent for histological analysis. The collected material was analyzed histologically and demonstrated mature bone, with areas of neoformation and deposition of bone matrix and the tomographic aspect was of a hypodense image inside the socket. Socket preservation realized with rhGH associated with Bio-Oss  was able to maintain the three-dimensional dimensions of the sockets, promoting neoformed bone with histological and radiographic features of maturation and was able to reduce the time of treatment.

Evaluation of human growth hormone (somatropin) in socket healing: a split-mouth randomized controlled trial

“…Our study also agrees with the study of Giacomin et al . 37 in preserving the dimensions of the alveolar bone in which he applied Bio-Oss with growth hormone to a patient who had a second premolar indicated for extraction on the upper jaw. Four months later, the results showed a preference for applying the material in preserving the dimensions of the alveolar bone.…”