Sodium Aminodiboranate, a New Reagent for Chemoselective Reduction of Aldehydes and Ketones to Alcohols

Abstract

Sodium aminodiboranate ((NaNH2(BH3)2, NaADBH) is a new member of the old borane family, which exhibits superior performance in chemoselective reduction. Experimental results show that NaADBH can rapidly reduce aldehydes and ketones to the corresponding alcohols in high-efficiency and selectivity under mild conditions. There are little steric and electronic effects on this reduction.

Chemo-selective CuPcS catalyzed reduction and esterification of carboxylic acid analogs

“…The results demonstrate superiority of this new approach to complete successful reductions of aromatic carboxylic acids. [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] This method offers several notable advantages. Initially, the catalyst utilized in the process can be easily recovered, allowing its reuse and minimizing waste.…”