2016
DOI: 10.1590/0037-8682-0266-2015
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Sodium nitroprusside has leishmanicidal activity independent of iNOS

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Cited by 8 publications
(5 citation statements)
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“…Kawakami and Orsini et al demonstrated that the release of NO from sodium nitroprusside (Figure ), an iron-containing complex, enhanced the in vitro antileishmanial activity in macrophages infected with L. amazonensis.…”
Section: Leishmaniasismentioning
confidence: 96%
See 1 more Smart Citation
“…Kawakami and Orsini et al demonstrated that the release of NO from sodium nitroprusside (Figure ), an iron-containing complex, enhanced the in vitro antileishmanial activity in macrophages infected with L. amazonensis.…”
Section: Leishmaniasismentioning
confidence: 96%
“…Kawakami and Orsini et al 203 demonstrated that the release of NO from sodium nitroprusside (Figure 42), an ironcontaining complex, enhanced the in vitro antileishmanial activity in macrophages infected with L. amazonensis. Sodium nitroprusside is a drug commonly used to lower blood pressure and to relieve heart failure.…”
Section: Chemical Reviewsmentioning
confidence: 99%
“…[ 25 27 ]. In the current study, SNP was chosen as an exogenous NO-generating agent [ 28 ] to treat ML of T . spiralis , and the differential expressions of proteins were identified by a label-free analysis coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS).…”
Section: Introductionmentioning
confidence: 99%
“…3-Nitrotyrosine is a well-established stable oxidative stress biomarker and a good predictor of the progression of some diseases, such as cardiovascular and neurodegenerative diseases [ 57 59 ]. The enhanced production of 3-nitrotyrosine was closely related to the enhanced microbicidal activity in Leishmania -infected macrophages [ 60 ]. A previous study revealed that 3-nitrotyrosine formation is a relevant indicator of antiparasitic activity [ 61 ].…”
Section: Discussionmentioning
confidence: 99%