Sodium quercetin-8-sulfonate trihydrate

Abstract

The organic anion of the title compound, {[Na(C15H9O10S)(H2O)2]·H2O}n {systematic name: poly[[diaqua­[μ-2-(3,4-dihy­droxy­phen­yl)-3,5,7-trihy­droxy-4-oxo-4H-chromene-8-sulfon­ato]­sodium] monohydrate]}, has a nearly planar structure. The Na atom is six-coordinated by O atoms, two from water mol­ecules and four from the anion. The dihedral angle between the ring systems in the anion is 10.1 (1)°. Intra­molecular O—H⋯S and O—H⋯O inter­actions occur. In the crystal structure, an extensive network of classical inter­molecular O—H⋯S and O—H⋯O hydrogen bonds forms layers along the c axis.

New sulfonic derivatives of quercetin as complexing reagents: synthesis, spectral, and thermal characterization

“…It is assumed that these water molecules are probably directly bonded with metal atoms [22]. This can be considered as expected result according to the crystal structure of NaQSA-8 presented in [15] where two water molecules are coordinated to sodium cation, and one is crystalline water. Moreover, the water molecules take part in inter-and intramolecular bonds with different interatomic distances.…”

“…Anal. Caled for C 15 No nitrogen was assayed in the compounds. The potentiometric titration was performed with a N5172 pHmeter with glass electrode.…”

“…NaQSA-8 compound is an excellent antagonist of Vif which has been found to be a novel hit of HIV-1 [14]. The synthesis of NaQSA-8 was already described, and the structure of the compound was determined by the X-ray analysis [15]. However, spectroscopic studies and studies of speciation in solution of the ligand were not carried out.…”

Potassium Complexes of Quercetin-5′-Sulfonic Acid and Neutral O-Donor Ligands: Synthesis, Crystal Structure, Thermal Analysis, Spectroscopic Characterization and Physicochemical Properties

“…So far, several papers have reported the crystal structures of sulfonic derivatives of different flavonoids and their complexes with alkali and transition metals (Table 1) [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]. The pattern of cation-anion interactions in these complexes depends on the position of the substituted sulfonic group and on the metal cation.…”

“…Moreover, some cations prefer to coordinate water molecules and form mononuclear complexes. It should be noted that ligands in the known complexes are derivatives containing sulfonic groups in the positions 6 [21][22][23][24][25][26]28], 8 [17][18][19][20] and 5′ [27] of the flavonoid skeleton (Table 1). Until now, the structure of only one complex with potassium cation has been determined [19].…”