Sodium sulfate–hydrogen peroxide–sodium chloride adduct: selective protocol for the oxidative bromination, iodination and temperature dependent oxidation of sulfides to sulfoxides and sulfones

Abstract

Sodium sulfate–hydrogen peroxide–sodium chloride adduct: selective protocols for anilines and sulfides oxidation.

Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

“…4-Bromo-phenylamine ( 1f ): The product was obtained as a grey solid in a yield of 70% (0.19 g). MP: 59–62 °C [44]. 1 H NMR (600 MHz, CDCl 3 ) δ 7.29 – 7.09 (m, 2H), 6.61 – 6.42 (m, 2H), 3.66 (d, J = 36.7 Hz, 2H).…”

A Fuel‐Driven Chemical Reaction Network Based on Conjugate Addition and Elimination Chemistry

“…Before testing this fuel‐driven cycle, some possible pitfalls associated to the chemistry in this cycle should be noted. Firstly, the oxidation of the sulfide to a sulfoxide requires a relatively strong oxidizing agent . The presence of such an oxidant may also lead to irreversible epoxidation or dihydroxylation of the enone double bond causing the removal of substrate from the cycle.…”

“…Firstly, the oxidation of the sulfide to a sulfoxide requires a relatively strong oxidizing agent. [16,17] The presence of such an oxidant may also lead to irreversible epoxidation or dihydroxylation of the enone double bond [18] causing the removal of substrate from the cycle. To avoid this potential side-reaction, maleimide was selected as the first enone in our cycle because it is less prone to oxidation.…”

Iodine(III)‐Mediated Free‐Aniline Iodination through Acetyl Hypoiodite Formation: Study of the Reaction Pathway

“…Examples of transtion-metal-free protocols require I 2 in polar solvents [17] or mixed with oxidants. [18] The use of ICl, [19] NIS [20] or the oxidation of the iodie anion from KI with KClO 3 [21] or H 2 O 2 [22] has been described as I + equivalent regents. Another important strategy for aniline iodination, makes use of the dichloroiodate anion.…”