SOFA score to assess the severity of the post-cardiac arrest syndrome

Cour, Martin; Bresson, Didier; Hernu, Romain; Argaud, Laurent

doi:10.1016/j.resuscitation.2016.03.001

Cited by 37 publications

(29 citation statements)

References 31 publications

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“…The SOFA score reflecting organ dysfunction in patients after ROSC is highly correlated with the outcome, similar to other studies, but our data are meaningful since prehospital SGA demonstrated an association with good neurologic outcomes despite adjusting SOFA. Our data suggest that, regardless of severity after resuscitation, SGA has a protective effect on the brain, which is more susceptible to hypoxic damage than other organs, by providing earlier and better oxygenation.…”

Section: Discussionsupporting

confidence: 89%

“…However, most of these studies did not adjust postresuscitation variables but adjusted only prehospital and resuscitation variables. Postresuscitation variables, such as organ dysfunction scores at survival admission and targeted temperature management (TTM) application, also have an influence of the neurologic outcomes of cardiac arrest victims . Therefore, we hypothesized that if we adjust postresuscitation variables, it would provide more clear evidences for the association of the prehospital use of SGA during CPR on the neurologic outcome of cardiac arrest victims.…”

mentioning

confidence: 99%

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Prehospital Supraglottic Airway Was Associated With Good Neurologic Outcome in Cardiac Arrest Victims Especially Those Who Received Prolonged Cardiopulmonary Resuscitation

Park

Kwon

Kim

et al. 2017

Academic Emergency Medicine

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Section: Discussionsupporting

confidence: 89%

mentioning

confidence: 99%

Prehospital Supraglottic Airway Was Associated With Good Neurologic Outcome in Cardiac Arrest Victims Especially Those Who Received Prolonged Cardiopulmonary Resuscitation

Park

Kwon

Kim

et al. 2017

Academic Emergency Medicine

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“…Kaukonen et al (22) also documented the inability of SIRS to stratify the severity of illness. SOFA score has been used as a front-line tool to grade disease severity in ICUs (20, 23, 24). We investigated the possibility of grading sepsis according to SOFA scores.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Performance Between Sepsis-1 and Sepsis-3 in ICUs in China

Cheng

Wang

et al. 2017

Shock

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The definition of sepsis was updated to sepsis-3 in February 2016. However, the performance of the previous and new definition of sepsis remains unclear in China. This was a retrospective multicenter study in six intensive care unit (ICUs) from five university-affiliated hospitals to compare the performance between sepsis-1 and sepsis-3 in China. From May 1, 2016 to June 1, 2016, 496 patients were enrolled consecutively. Data were extracted from the electronic clinical records. We evaluated the performance of sepsis-1 and sepsis-3 by measuring the area under the receiver operating characteristic curves (AUROC) to predict 28-day mortality rates. Of 496 enrolled patients, 186 (37.5%) were diagnosed with sepsis according to sepsis-1, while 175 (35.3%) fulfilled the criteria of sepsis-3. The AUROC of systemic inflammatory response syndrome (SIRS) is significantly smaller than that of sequential organ failure assessment (SOFA) (0.55 [95% confidence interval, 0.46–0.64] vs. 0.69 (95% confidence interval, 0.61–0.77], P = 0.008) to predict 28-day mortality rates of infected patients. Moreover, 5.9% infected patients (11 patients) were diagnosed as sepsis according to sepsis-1 but not to sepsis-3. The APACHE II, SOFA scores, and mortality rate of the 11 patients were significantly lower than of patients whose sepsis was defined by both the previous and new criteria (8.6±3.5 vs. 16.3±6.2, P = < 0.001; 1 (0–1) vs. 6 (4–8), P = <0.001; 0.0 vs. 33.1%, P = 0.019). In addition, the APACHE II, length of stay in ICU, and 28-day mortality rate of septic patients rose gradually corresponding with the raise in SOFA score (but not the SIRS score). Sepsis-3 performed better than sepsis-1 in the study samples in ICUs in China.

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“…[18][19][20][21] Contrarily, both the the Sepsis-related Organ Failure Assessment (SOFA) score and the Pittsburg Cardiac Arrest Category, based on SOFA in combination with neurological symptoms is able to predict mortality and morbidity. [9,[22][23][24] Therefore, it is plausible that an increasing degree of organ support, and in particular RRT, reflects a severely injured OHCA-patient, explaining the distinct prognostic impact of RRT found in this study. Last, our study findings may reflect that the in-hospital course in itself affects the ability to return to work.…”

Section: Accepted Manuscriptmentioning

confidence: 63%