Sultana, N. (2015) Imprecise knowledge based design and development of titanium alloys for prosthetic applications.Journal Abstract Imprecise knowledge on the composition-processing-microstructure-property correlation of titanium alloys combined with experimental data are used for developing rule based models for predicting the strength and elastic modulus of titanium alloys. The developed models are used for designing alloys suitable for orthopaedic and dental applications. Reduced Space Searching Algorithm is employed for the multi-objective optimization to find composition, processing and microstructure of titanium alloys suitable for orthopaedic applications. The conflicting requirements attributes of the alloys for this particular purpose are high strength with low elastic modulus, along with adequate biocompatibility and low costs. The 'Pareto' solutions developed through multi-objective optimization show that the preferred compositions for the fulfilling the above objectives lead to β or near β alloys. The concept of decision making employed on the solutions leads to some compositions, which should provide better combination of the required attributes. The experimental development of some of the alloys has been carried out as guided by the model-based design methodology ©2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ 2 presented in this research. Primary characterizations of the alloys show encouraging results in terms of the mechanical properties.