Soft, Erythematous Nodule of the Ankle with a String of Pearls Vascular Pattern: A Quiz

Non-invasive Imaging Techniques for the Diagnosis of Clear Cell Acanthomas: Dermoscopy, Reflectance Confocal Microscopy and Line-Field Confocal Optical Coherence Tomography

“…Glomerular blood vessels and red clods in a reticular and curvilinear pattern, resembling a pearl necklace, with combined thin and thick white intersecting lines are typical clues for the diagnosis. The primary clinical and pathological differential diagnoses that must be considered include eccrine poroma, basal cell carcinoma, squamous cell carcinoma, amelanotic melanoma, pyogenic granuloma, lichenoid keratosis, inflamed seborrheic keratosis, and psoriasis [4]. For that reason, noninvasive imaging techniques are useful for a better evaluation to avoid excisional biopsy for histopathological examination.…”