Abstract-A system-level model for power control in the uplink of direct-sequence code-division multiple access (DS-CDMA) cellular networks is presented. The model takes into account the effects of the closed loop, namely average transmit power rise, power headroom, and variable soft hand-off gains, which are not considered in existing power control models. The power control problem is analyzed in this setting, and a number of properties are derived which generalize results from the classical model without closed-loop effects. Based on this analysis, an algorithm is given that determines required transmit powers taking into account these effects. This algorithm is a generalization of classical iterative algorithms without closed-loop effects. Finally, simulation results are presented to assess the validity of the approach.