SummaryIn general, cascaded H‐bridge multilevel inverters (CHB‐MLI) are typically operated with either symmetrical or asymmetrical input DC sources, set at predefined specific ratios such as binary (1:2) or trinary (1:3) in the case of asymmetry, to achieve the desired output voltage waveform. However, if any DC source fails to provide the predefined voltage magnitude, or CHB‐MLIs with unspecified DC source ratios are utilized, the output voltage waveform may exhibit unequal magnitudes between consecutive levels, thereby causing a significant increase in total harmonic distortion (THD). Conventionally, to mitigate this effect, the corresponding H‐bridge is bypassed through zero voltage switching, which leads to an additional burden on the remaining H‐bridges to serve the same load. To reduce the burden on the remaining cells and improve the THD profile of the inverter, this article proposes a novel method for CHB‐MLI with varying DC magnitudes. It aims to enhance the quality of the output voltage waveform by strategically selecting optimum voltage levels rather than utilizing all available levels when CHB‐MLI has unspecified or variable DC sources. This approach can achieve a more balanced distribution of voltage magnitudes across successive levels by eliminating redundant states. Moreover, the proposed technique can reduce switch losses and enhance the converter's efficiency. The proposed method is validated through MATLAB/Simulink software simulations, followed by experimental verification.