2019
DOI: 10.1016/j.molliq.2019.111388
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Soft-templated fabrication of antihypertensive nano-Irbesartan: Structural and dissolution evaluation

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Cited by 25 publications
(31 citation statements)
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“…The final formulation contained ethyl acetate (18.0%), ethanol (25.0%), brij-35 (25.0%), and water (32.0%) and was marked for further analysis, as shown in Figure . As supported by previous studies, a high proportion of water (32.0 wt %) in this formulation, that is, >25 wt %, shows the development of an o/w μE. ,, Table lists some measured physical parameters of the optimum EZM-free μE, EZM-loaded μE, and EZM-NPs.…”
Section: Resultssupporting
confidence: 60%
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“…The final formulation contained ethyl acetate (18.0%), ethanol (25.0%), brij-35 (25.0%), and water (32.0%) and was marked for further analysis, as shown in Figure . As supported by previous studies, a high proportion of water (32.0 wt %) in this formulation, that is, >25 wt %, shows the development of an o/w μE. ,, Table lists some measured physical parameters of the optimum EZM-free μE, EZM-loaded μE, and EZM-NPs.…”
Section: Resultssupporting
confidence: 60%
“…Physical conformation of EZM-NPs and EZM-bulkpowder was measured by powder XRD. ,,, XRD (Bruker, D2-Phaser) measurement was carried out in the 10–70 range of 2θ (degree) with 0.02° variation with a scan rate of 4°/min. The sample weight was about 0.5 g. The diffraction grating of the EZM-bulkpowder was co-related with that of its nanodispersion.…”
Section: μE Characterizationmentioning
confidence: 99%
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“…However, they showed superior anti-inflammatory efficacy than free-methotrexate, as well [ 68 ]. Other nanoplatforms that inhibit TNF-α are surface charge tuneable (PEG5K-b-PLGA10K) NPs [ 69 ], gold NPs [ 70 ], nanodiamonds [ 47 ], Chitosan-Tripolyphosphate NPs [ 71 ], Polycaprolactone NPs [ 72 ], Magnetic nanocomposite particles [ 73 ], Zein NPs [ 74 ], Melatonin/Polydopamine Nanostructures [ 75 ], Polyurethane-chitosan copolymer [ 76 ], Nanocrystalline suspension [ 77 ], Lyophilized non-aggregated NP of Irbesartan (IBS-NPs) [ 78 , 79 ]and Solid lipid NPs [ 80 ].
Figure 3 The anti-viral effect of Ag 2 S nanoclusters.
…”
Section: Preclinical Assessment Of Nps Used For Covid-19 Therapymentioning
confidence: 99%
“…Enhanced delivery of lipophilic, hydrophilic, and amphiphilic drugs can be achieved through μE formulation. The main advantages of μE formulations are considered to be the ingestion of a large amount and an enormous increase in the solubilization of the drug. The μE formulation also plays a critical role in the stability and absence of aggregation of the drug, which further corresponds to the steady-state release of the drug. …”
Section: Introductionmentioning
confidence: 99%