Extra skeletal soft tissue chondroma (ESSC) is very rare slowly growing benign tumours usually occur in hands and feet. Lesion must be differentiated from other benign and malignant lesions in these locations by clinical, radiological, cytological and histopathological examination for proper management of such benign entity. A case is presenting here in a thirty five years old lady suffering from similar type of lesion over right thumb diagnosed preoperatively by fine needle aspiration cytology because of rarity. Diagnosis was confirmed by surgical excision and histopathological examination.International Journal of Human and Health Sciences Vol. 02 No. 03 July’18. Page : 164-166