Soft Tissue Tumors of the Mediastinum

Pathologic features of head and neck adult rhabdomyosarcoma: Case series

“…It arises most commonly in the skeletal muscles of the thigh [ 9 ]. The spindle cell/sclerosing rhabdomyosarcoma accounts for 3–10 % of RMSs [ 10 ]. It is commonly found in both children and adults and the head and neck region is the most common site of its involvement, followed by the extremities [ 10 ].…”

“…SPRMS was not included in previous studies, most likely because it was considered a variant of Embryonal RMS. However, the WHO classification [ 10 ] (5th Edition, 2020) has now provisionally listed SRMS as a separate subtype.…”

“…It exhibits prominent hyalinization/sclerosis, with tumor cells arranged in cords, nests, micro alveoli, or trabeculae. Sclerosing areas may mimic osteosarcoma due to the extensive matrix formation [ 10 ]. Primitive undifferentiated areas with round cells and rhabdomyoblasts with elongated eosinophilic tails and cross-striations can be observed in some cases.…”