Soft-tissue venous malformations in children: percutaneous sclerotherapy with Ethibloc.

Abstract

Thirty-eight children with soft-tissue venous malformations (VMs) were treated with percutaneous injection of a new fibrosing agent (Ethibloc). The technique, results, side effects, and complications are detailed. Direct puncture of the VM allows evaluation of the draining venous system and direct injection of Ethibloc. This procedure alone or associated with surgery led to achievement of good or excellent results in 74% of the cases (complete cure in 50%), with minimal side effects and no major complications.

Treatment of Venous Malformations With Sclerosant in Microfoam Form

“…Sclerotherapy is an alternative method of treatment for venous malformations, 7 and is used to reduce the size of the lesion, preoperatively as a support to surgery or as a postoperative complement. Sclerosants destroy the vascular endothelium through different mechanisms: chemical agents (iodine or alcohol 8 ), osmotic agents (salicylates or hypertonic saline), and detergents (morrhuate sodium, 9 sodium tetradecyl sulfate, 10 polidocanol, 11 and diatrizoate sodium 12 ), which change the surface tension of the cell, producing tissue maceration. There is no safe sclerosant, and all are associated with complications of different degrees of severity.…”

Polidocanol sclerotherapy for painful venous malformations: evaluation of safety and efficacy in pain relief

“…Percutaneous sclerotherapy for venous malformations (VMs) has recently been explored as a successful alternative to surgery [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Traditionally, absolute ethanol has been the agent of choice for sclerotherapy [1][2][3][4][5][6][7][8][9].…”

Intralesional Sclerotherapy With 3% Sodium Tetradecyl Sulphate in Cutaneous Vascular Malformation : A Retrospective Study

“…[16] Ethibloc has also been utilized for sclerotherapy but the drawback of lack of commercial availability and necessity for GA precludes its use. [17] The sodium tetradecyl sulfate has been used extensively for sclerotherapy of varicose veins since it was first described by Reiner in 1946. [18] Many of the previous studies have noted good results achieved in vascular malformations with the use of this substance.…”