Software Application Profile: DeGAUSS – Decentralized Geomarker Assessment for Multi-Site Studies

Abstract

Motivation: DeGAUSS is a software application for geocoding and geomarker assessment that circumvents barriers related to cost and reproducibility presented by conventional approaches. Most importantly, DeGAUSS safeguards protected health information (PHI), such as a mailing address. Implementation: DeGAUSS is implemented as a family of software containers with R code, geospatial software libraries, and geographic data. The containers are available in online repositories and accessed by users through the command line. It is free and open-source software under continuous development. General Features: DeGAUSS operates locally, ensuring that PHI is not passed over the internet, and reproducibly, which allows for easier operation in multi-site studies. In addition to geocoding, software containers are available for many geomarkers commonly utilized in epidemiological studies, including data related to the census, meteorology, land cover, greenspace, roadways, access to care, and air pollution. Availability: This software is freely available via “GitHub Container Registry” at https://degauss.org/.