Software FIACRE: Bioprocess monitoring on the basis of flow injection analysis using simultaneously a urea optode and a glucose luminescence sensor

Busch, Manfred; Höbel, W.; Polster, Jürgen

doi:10.1016/0168-1656(93)90078-2

Cited by 15 publications

(6 citation statements)

References 24 publications

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“…Glucose biosensors utilizing optical pH sensors explore classical indicator chemistry, utilize pH-dependent absorption changes of polyaniline (section on conjugated polymers), or the swelling of amino-modified hydrogel as induced by pH changes . Biosensors for penicillin ,− utilize hydrolysis of the antibiotic catalyzed by penicillinase (β-lactamase). This results in the formation of penicilloic acid and therefore a drop of the pH value.…”

Section: Selected Applications Of Optical Ph Sensorsmentioning

confidence: 99%

Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

2020

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This is the first comprehensive review on methods and materials for use in optical sensing of pH values and on applications of such sensors. The Review starts with an introduction that contains subsections on the definition of the pH value, a brief look back on optical methods for sensing of pH, on the effects of ionic strength on pH values and p K a values, on the selectivity, sensitivity, precision, dynamic ranges, and temperature dependence of such sensors. Commonly used optical sensing schemes are covered in a next main chapter, with subsections on methods based on absorptiometry, reflectometry, luminescence, refractive index, surface plasmon resonance, photonic crystals, turbidity, mechanical displacement, interferometry, and solvatochromism. This is followed by sections on absorptiometric and luminescent molecular probes for use pH in sensors. Further large sections cover polymeric hosts and supports, and methods for immobilization of indicator dyes. Further and more specific sections summarize the state of the art in materials with dual functionality (indicator and host), nanomaterials, sensors based on upconversion and 2-photon absorption, multiparameter sensors, imaging, and sensors for extreme pH values. A chapter on the many sensing formats has subsections on planar, fiber optic, evanescent wave, refractive index, surface plasmon resonance and holography based sensor designs, and on distributed sensing. Another section summarizes selected applications in areas, such as medicine, biology, oceanography, bioprocess monitoring, corrosion studies, on the use of pH sensors as transducers in biosensors and chemical sensors, and their integration into flow-injection analyzers, microfluidic devices, and lab-on-a-chip systems. An extra section is devoted to current challenges, with subsections on challenges of general nature and those of specific nature. A concluding section gives an outlook on potential future trends and perspectives.

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Section: Selected Applications Of Optical Ph Sensorsmentioning

confidence: 99%

Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

2020

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“…Penicilloate and protons are produced from penicillin in the enzymatic hydrolysis catalyzed by penicillinase. The decrease in pH is monitored by changes of absorption (reflectance) − or emission intensity − of pH indicators. Fluorescein-derived indicators were used almost exclusively in order to monitor pH changes in neutral media.…”

Section: 3 Other Enzyme-based Biosensorsmentioning

confidence: 99%

Optical Biosensors

2008

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“…Various computer programs for large-scale bioprocess control and optimization have been developed as well as software for simple laboratory routine analysis [134]. In comparison, software can hardly be found that works on laboratory scale and provides the control of complex FIA systems, multisubstrate determination, data evaluation as well as minimal process control abilities.…”

Section: Chemiluminescencementioning

confidence: 99%

Recent Development in Optical Chemical Sensors Coupling with Flow Injection Analysis

Ojeda

Rojas

2006

Sensors

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Abstract:Optical techniques for chemical analysis are well established and sensors based on these techniques are now attracting considerable attention because of their importance in applications such as environmental monitoring, biomedical sensing, and industrial process control. On the other hand, flow injection analysis (FIA) is advisable for the rapid analysis of microliter volume samples and can be interfaced directly to the chemical process. The FIA has become a widespread automatic analytical method for more reasons; mainly due to the simplicity and low cost of the setups, their versatility, and ease of assembling. In this paper, an overview of flow injection determinations by using optical chemical sensors is provided, and instrumentation, sensor design, and applications are discussed. This work summarizes the most relevant manuscripts from 1980 to date referred to analysis using optical chemical sensors in FIA.

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Software FIACRE: Bioprocess monitoring on the basis of flow injection analysis using simultaneously a urea optode and a glucose luminescence sensor

Cited by 15 publications

References 24 publications

Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

Optical Biosensors

Recent Development in Optical Chemical Sensors Coupling with Flow Injection Analysis

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