The average yield of bulb onions is still quite low. The purpose of this study was to improve the techniques and methods of cultivating onions using new generation preparations against the background of N180P60K60 in a drip irrigation method. To achieve the objective of this study, field surveys, observations and measurements were carried out using generally accepted methods. The experimental data obtained from the studies were processed using analysis of variance in Excel, which is part of the Microsoft Office installation package. Field experience included both background application of mineral fertilizers, as well as integrated nutrition of plants with Aminofol Plus and Novosil bulb onion growth stimulants and its biological protection with drugs Gaitang, KE, Akzifor, KE and with Monarch, VDG preparations. According to the results of tests carried out in the 3rd soil-climatic zone, they positively influenced the growth processes and yield of the cultivated crop. The use of this scheme gave a significant increase in the number of commercial bulbs and the weight of commercial bulbs relative to the control version, which significantly affected the yield, which was 121.8 tons/ha (commercial yield). Based on the results of the obtained experimental data, the following was identified, the difference in yield is due to the effect of drugs that have a positive effect on the variety and hybrid of onions, which are under study.