Sol-gel transition induced by alumina nanoparticles in a model pulmonary surfactant

N,N,N-Trimethyl chitosan as a permeation enhancer for inhalation drug delivery: Interaction with a model pulmonary surfactant

“…In the lower part of the figure, it is possible to observe a multilamellar vesicle, however of a smaller size compared to the native ones. These results bear some similarities with those obtained in the case of the addition of cationic Al2O3 nanoplatelets to Curosurf®, a result that was also accounted for by electrostatic-driven nanoplatelets adsorption to the membranes [74]. In the latter case, the alumina nanoplatelets do not carry amines on their surface but Al-OH2 + hydration complexes of high charge density (+7.3e nm -2 ) [38,75].…”