The particle and radiation environment in cis-lunar space is becoming increasingly important as more and more hardware and human assets occupy various orbits around the Earth and space exploration efforts turn to the Moon and beyond. Since 2020, the total number of satellites in orbit has approximately doubled, highlighting the growing dependence on space-based resources. Through NASA's upcoming Artemis missions, humans will spend more time in cis-lunar space than ever before supported by the expansive infrastructure required for extended missions to the Moon, including a surface habitat, a communications network, and the Lunar Gateway -a space station which will orbit the Moon. Cis-lunar space starts at the top of the Earth's atmosphere and extends out to the orbit of the Moon, including the ionosphere, magnetosphere, free space, and the lunar surface. This paper focuses on galactic cosmic rays (GCRs) and solar energetic particles (SEPs) that create a dynamic and varying radiation environment within these regions. GCRs are particles of hundreds of MeV/nucleon (MeV/n) and above generated in highly energetic astrophysical environments in the Milky Way Galaxy, such as supernovae and pulsars, and beyond. These particles impinge isotropically on the heliosphere and are filtered down to 1 AU, experiencing modulation in energy and intensity on multiple timescales, from hours to decades, due to the solar magnetic cycle and other transient phenomena. SEPs are particles with energies up to thousands of MeV/n that are accelerated in eruptive events on the Sun and flood the inner heliosphere causing sudden and drastic increases in the particle environment on timescales of minutes to days. This paper highlights a current and prospective future gap in energetic particle measurements in the hundreds of MeV/n. We recommend key observations near Earth to act as a baseline as well as distributed measurements in the heliosphere, magnetosphere, and lunar surface to improve the scientific understanding of these particle populations and sources.