solated Fournier’s Gangrene of Penis: Case Series

Case Report on Fournier's Gangrene

“…The synergistic microbial activity results in production of various exotoxins and enzymes like collagenase, heparinase, hyaluronidase, streptokinase and streptodornase, which lead to tissue destruction and spread of infection. The aetiological factors of Fournier gangrene are obesity 9 , diabetes mellitus, abnormal sexual practices, alcohol abuse [9][10][11][12][13][14][15] , infection of gastrointestinal tract 3 , tissue ischemia [3][4][5][6][7][8][9][10][11][12] . When it comes to children the main aetiological factor is diaper rash 17 , pelvic injury, omphalitis, localised abscess, circumcision [24][25][26][27] .…”

“…When it comes to children the main aetiological factor is diaper rash 17 , pelvic injury, omphalitis, localised abscess, circumcision [24][25][26][27] . The most important predisposing factors that we encounter among the patients are age, diabetes mellitus, rectal cancer, chronic alcohol abuse, malignancy [13][14][15][16] ,parentral drug use, malnutrition, extreme ages, atrial hypertention, chemo radiotherapy [24][25][26] . Predisposing factors for mortality in patients with FG is female gender, which is due to the association with the frequent involvement of retroperitoneal and abdominal cavity in inflammatory process 13 .…”

“…The most important predisposing factors that we encounter among the patients are age, diabetes mellitus, rectal cancer, chronic alcohol abuse, malignancy [13][14][15][16] ,parentral drug use, malnutrition, extreme ages, atrial hypertention, chemo radiotherapy [24][25][26] . Predisposing factors for mortality in patients with FG is female gender, which is due to the association with the frequent involvement of retroperitoneal and abdominal cavity in inflammatory process 13 . The immunocompetent patients presenting with the FG, a thorough evaluation for underlying disease should be done.…”

“…This disease is infective in origin 11 . The Aetiology includes abnormal sexual practices, parentral drug abuse, trauma, insect bite, prior surgical procedures in the perenial region, burns (11)(12)(13)(14)(15)(16)(17)(18) . Predisposing factors of FG's include Diabetes Mellitus , alcoholism, immunosuppression, tobacco abuse, chemotherapy, radiography, atrial Hypertension 28,29,30 .…”

“…Diagnosis includes ultrasonography, CTscan , MRI, radiography, blood culture, complete blood count 1 . Management of FG includes resustation, broad spectrum , intravenousantibiotics, surgical debridement and supportive therapy 13 . The present case report is of particular importance as it describes a case of FG with Type-1 Diabetes Mellitus.…”