“…These last complexities can only be tackled by resorting to complex CFD-based two-phase simulations, as done by , who employed RANS for the liquid phase and Lagrangian DPM for the particles, as well as by Hartman et al (2006), who resorted to LES and an Eulerian-Lagrangian approach involving particle size distribution as well as particle-particle and particle-walls interactions, so usefully getting extremely detailed information, but clearly at the cost of an extremely high simulation burden and suffering from a substantial lack of experimental evidence for model details validation. As concerns this last aspect, advanced experimental techniques such as Electrical Resistance Tomography (ERT, Carletti et al, 2018;Montante et al, 2019) and Laser Sheet Image Analysis (LSIA, Tamburini et al, 2013;Busciglio et al, 2010) have started being employed for getting local features of the stirred twophase mixtures, including the case of dissolving particles, and may provide the experimental information needed to validate complex CFD models. Apart from these last developments, most of the previously quoted dissolution models adopt a concentrated parameter approach for the interfacial and bulk concentrations as well as for mass transfer coefficient and particle size (i.e.…”