Solid–Liquid Equilibrium of l-Thioproline in Nine Neat Solvents and Water + Acetonitrile Binary Solvent System from 283.15 to 323.15 K: Solubility Determination and Data Modeling

Abstract

The data on the solubility of L-thioproline in a mole fraction scale in nine individual solvents (water, methanol, ethanol, isopropanol, acetone, acetonitrile, dichloromethane, ethyl acetate, and 1,4-dioxane) and one binary solvent mixture of water + acetonitrile was measured by a static gravimetric method from 283.15 to 333.15 K. Whether or not a neat or binary solvent system is used, the solubility is nonlinearly positively correlated with the experimental temperatures. At a given temperature, the solubility presents an order of water > acetone ≈ 1,4-dioxane > dichloromethane ≈ ethanol ≈ ethyl acetate > methanol > isopropanol > acetonitrile, which is a result of the multiple influences of many factors related to intermolecular interactions. Four thermodynamic models, including the modified Apelblat, Yaws, Jouyban−Acree, and Apelblat−Jouyban−Acree models were employed for correlating the solubility data, and the results show a satisfactory fitting effect for each model.

Solubility Measurement and Model Calculation of Fluorene in Six Binary Solvents from 288.15 to 328.15 K

“…The correlation between solvent composition and the solubility of the solute in the binary solvent under different temperature environments can be expressed by the Jouyban–Acree model and is shown as eq − where ln x 1, T and ln x 2, T are the solubilities of fluorene in the corresponding pure solvents and can be descirbed through the modified Apelblat equation (eq ), thus the modified Apelblat–Jouyban–Acree model can also be described as eq , where x 1 represents the mole fraction solubility of fluorene; ω 1 and ω 2 are the mass fractions of o -xylene and methanol (or ethanol, isopropyl alcohol, n -propanol, 2-butanol, and n -butanol) in the corresponding binary solvents, ω 1 = 1 – ω 2 ; and j i ( j 0 , j 1 , j 2 ) are the parameters of the model.…”

Solubility and Hansen Solubility Parameter of Nα-Carbobenzyloxy-l-Arginine in Twelve Individual Solvents from 283.15 to 323.15 K

“…The solubility of N α -carbobenzyloxy- l -arginine in 12 solvents was determined by the static gravimetric method. The detailed process of solubility measurement has been described in the Supporting Information, which has been described and verified in our previous studies. − The mole fraction solubility of N α -carbobenzyloxy- l -arginine ( x 1 ) can be calculated using eq . …”

Study on the solid–liquid equilibrium and thermodynamic model of the l-phenylalanine + l-tryptophan + water system

“…3,4 For example, L-methyltryptophan, a derivative of L-tryptophan, has been shown to have tumor suppressive effects, especially in chemotherapy. [5][6][7] In the liver, the amount of methionine can be used to diagnose the liver's ability to utilize peptides. Consequently, the study of amino acids has gained recognition and favor among numerous scientific researchers.…”