Underwater vehicles are currently the most effective equipment for exploring ocean mineral resources, whose movement performance been paid more attention by many scholars. According to the underwater vehicle integrating with 19A/Ka4-55 type ducted propellers, this paper researches the hydrodynamic characteristics of the overall vehicle in water under different movement states by leveraging CFD method. Combining structural grids and non-structural grids, an underwater vehicle model with 19A/Ka4-55 ducted propellers is constructed according to the designed propeller arrangement. A specific test rig is set up to verify the accuracy and effectiveness of the CFD method. Finally, the hydrodynamic performance of the integral underwater vehicle carrying the ducted propeller under different working conditions is further analysed. The result suggests that the vehicle still has sufficient propulsion at the inflow velocity of 1 m/s in the forward direction. Under ascending condition, the maximum running speed of the operating vehicle is around 0.5 m/s. It also has shown the feasibility and necessity of hydrodynamic performance analysis.